Preventing and controlling influenza virus infection remains a global public health
challenge, as it causes seasonal epidemics to unexpected pandemics. These infections are …

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This manuscript presents the latest algorithmic and methodological developments to the
structure‐based design program DOCK 6.7 focused on an updated internal energy function …

Considerable progress has been made toward understanding the structural basis of the
interaction of the two major surface glycoproteins of influenza A virus with their common …

Nucleic-acid aptamers have the molecular recognition properties of antibodies, and can be
isolated robotically for high-throughput applications in diagnostics, research and …

Shorebirds and waterfowls are believed to be the reservoir hosts for influenza viruses,
whereas swine putatively act as mixing vessels. The recent identification of two influenza …

The threat of a major human influenza pandemic, in particular from highly aggressive strains
such as avian H5N1, has emphasized the need for therapeutic strategies to combat these …

4-Amino-and 4-guanidino-4 H-pyran-6-carboxamides 4 and 5 related to zanamivir (GG167)
are a new class of inhibitors of influenza virus sialidases. Structure− activity studies reveal …

Influenza is a long-standing health problem. For treatment of seasonal flu and possible
pandemic infections, there is a need to develop new anti-influenza drugs that have good …

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comprehensive source on medicinal chemistry and drug discovery and development. This …