Stress and cancer: mechanisms, significance and future directions

A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Perioperative events influence cancer recurrence risk after surgery

JG Hiller, NJ Perry, G Poulogiannis, B Riedel… - Nature reviews Clinical …, 2018 - nature.com
Surgery is a mainstay treatment for patients with solid tumours. However, despite surgical
resection with a curative intent and numerous advances in the effectiveness of (neo) …

Exploiting the critical perioperative period to improve long-term cancer outcomes

M Horowitz, E Neeman, E Sharon… - Nature reviews Clinical …, 2015 - nature.com
Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

CSD Roxburgh, DC McMillan - Future oncology, 2010 - Taylor & Francis
Disease progression in cancer is dependent on the complex interaction between the tumor
and the host inflammatory response. There is substantial evidence in advanced cancer that …

Potential impact of invasive surgical procedures on primary tumor growth and metastasis

M Alieva, J van Rheenen, MLD Broekman - Clinical & experimental …, 2018 - Springer
Surgical procedures such as tumor resection and biopsy are still the gold standard for
diagnosis and (determination of) treatment of solid tumors, and are prognostically beneficial …

Impact of anastomotic leakage on long-term survival of patients undergoing curative resection for colorectal cancer

CS McArdle, DC McMillan, DJ Hole - Journal of British Surgery, 2005 - academic.oup.com
Background The impact of anastomotic leakage on immediate postoperative mortality in
patients undergoing potentially curative resection for colorectal cancer is well recognized. Its …

Excisional surgery for cancer cure: therapy at a cost

JC Coffey, JH Wang, MJF Smith… - The lancet …, 2003 - thelancet.com
Excisional surgery is one of the primary treatment modalities for cancer. Minimal residual
disease (MRD) is the occult neoplastic disease that remains in situ after curative surgery …

Systemic inflammatory response predicts survival following curative resection of colorectal cancer

DC McMillan, K Canna, CS McArdle - Journal of British Surgery, 2003 - academic.oup.com
Background Some studies have shown that the presence of a systemic inflammatory
response, as evidenced by raised circulating concentrations of C-reactive protein (CRP) …

[HTML][HTML] The effects of surgery on tumor growth: a century of investigations

R Demicheli, MW Retsky, WJM Hrushesky, M Baum… - Annals of oncology, 2008 - Elsevier
A few clinical investigations suggest that while primary breast cancer surgical removal
favorably modifies the natural history for some patients, it may also hasten the metastatic …

Does the mobilization of circulating tumour cells during cancer therapy cause metastasis?

OA Martin, RL Anderson, K Narayan… - Nature reviews Clinical …, 2017 - nature.com
Despite progressive improvements in the management of patients with locoregionally
confined, advanced-stage solid tumours, distant metastasis remains a very common—and …