The year 2004 represents a milestone for the biosensor research community: in this year,
over 1000 articles were published describing experiments performed using commercially …

With the approval of 2 radiolabeled antibody products for the treatment of non-Hodgkin's
lymphoma (NHL), radioimmunotherapy (RIT) has finally come of age as a new therapeutic …

Abstract This “Magnum Opus” accentuates my lifelong belief that the future of science is in
the interdisciplinary approach to hypotheses formulation and problem solving. Inspired by …

The article reviews the background and current status of pretargeting for cancer imaging and
therapy with radionuclides. Pretargeting procedures were introduced∼ 20 years ago as an …

Hybrid nanomaterials composed of synthetic and biological building blocks possess high
potential for the design of nanomedicines. The use of self-assembling nanomaterials as “bio …

Due to their favorable chemical features, Re and Tc complexes have been widely used for
the development of new therapeutic agents and imaging probes to solve problems of …

Oncology Book of 2011, British Medical Association's Medical Book Awards Awarded first
prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody …

Pretargeting is often used as a tumor targeting strategy that provides much higher tumor to
non-tumor ratios than direct-targeting using radiolabeled antibody. Due to the multiple …

Detection of a new or recurrent breast cancer lesion relies on physical examination and
imaging studies, primarily mammography, followed by histopathologic evaluation of biopsy …

While 188Re has been used successfully in mice for tumor radiotherapy by MORF/cMORF
pretargeting, previous radiolabeling of the amine-derivatized cMORF with 90Y, a longer …