Lumbar disc herniation
Abstract Purpose of Review Substantial advancements have been made in the cause,
diagnosis, imaging, and treatment options available for patients with lumbar disc herniation …
diagnosis, imaging, and treatment options available for patients with lumbar disc herniation …
Current concepts for lumbar disc herniation
Purpose To present the pathophysiology, biology, clinical presentation, diagnosis, and
current treatment options for lumbar disc herniation. Methods A thorough literature search …
current treatment options for lumbar disc herniation. Methods A thorough literature search …
Advancing the cellular and molecular therapy for intervertebral disc disease
The healthy intervertebral disc (IVD) fulfils the essential function of load absorption, while
maintaining multi-axial flexibility of the spine. The interrelated tissues of the IVD, the annulus …
maintaining multi-axial flexibility of the spine. The interrelated tissues of the IVD, the annulus …
Immuno-modulatory effects of intervertebral disc cells
P Bermudez-Lekerika, KB Crump… - Frontiers in cell and …, 2022 - frontiersin.org
Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …
[HTML][HTML] Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy
X Zhang, Y Hu, P Cheng, H Zhou, X Chen… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process
associated with low back pain (LBP). The pathogenesis is complicated, and the main …
associated with low back pain (LBP). The pathogenesis is complicated, and the main …
[HTML][HTML] Genetic factors in intervertebral disc degeneration
Y Feng, B Egan, J Wang - Genes & diseases, 2016 - Elsevier
Low back pain (LBP) is a major cause of disability and imposes huge economic burdens on
human society worldwide. Among many factors responsible for LBP, intervertebral disc …
human society worldwide. Among many factors responsible for LBP, intervertebral disc …
Inflammatory mediators in intervertebral disk degeneration and discogenic pain
Although degeneration of the intervertebral disk has historically been described as a
misbalance between anabolic and catabolic factors, the role of inflammatory mediators has …
misbalance between anabolic and catabolic factors, the role of inflammatory mediators has …
Genetic polymorphisms associated with intervertebral disc degeneration
BACKGROUND CONTEXT: Disc degeneration (DD) is a multifaceted chronic process that
alters the structure and function of the intervertebral discs and can lead to painful conditions …
alters the structure and function of the intervertebral discs and can lead to painful conditions …
lnc RNA s: novel players in intervertebral disc degeneration and osteoarthritis
WK Chen, XH Yu, W Yang, C Wang, WS He… - Cell …, 2017 - Wiley Online Library
The term long non‐coding RNA (lnc RNA) refers to a group of RNA s with length more than
200 nucleotides, limited protein‐coding potential, and having widespread biological …
200 nucleotides, limited protein‐coding potential, and having widespread biological …
Genetic alterations in intervertebral disc disease
Background Intervertebral disc degeneration (IVDD) is considered a multifactorial disease
that is influenced by both environmental and genetic factors. The last two decades of …
that is influenced by both environmental and genetic factors. The last two decades of …