Chagas disease
A Rassi, JA Marin-Neto - The Lancet, 2010 - thelancet.com
Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan
Trypanosoma cruzi, and was discovered in 1909. The disease affects about 8 million people …
Trypanosoma cruzi, and was discovered in 1909. The disease affects about 8 million people …
Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity
B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
widely recognized. At present, T. cruzi is partitioned into seven discrete ty** units (DTUs) …
An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment
J Martín-Escolano, C Marín, MJ Rosales… - ACS Infectious …, 2022 - ACS Publications
Chagas disease (CD) is a parasitic, systemic, chronic, and often fatal illness caused by
infection with the protozoan Trypanosoma cruzi. The World Health Organization classifies …
infection with the protozoan Trypanosoma cruzi. The World Health Organization classifies …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Trypanosoma cruzi surface mucins: host-dependent coat diversity
CA Buscaglia, VA Campo, ACC Frasch… - Nature Reviews …, 2006 - nature.com
The surface of the protozoan parasite Trypanosoma cruzi is covered in mucins, which
contribute to parasite protection and to the establishment of a persistent infection. Their …
contribute to parasite protection and to the establishment of a persistent infection. Their …
Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillos hosts of Trypanosoma cruzi II, including hybrids
M Yeo, N Acosta, M Llewellyn, H Sánchez… - International journal for …, 2005 - Elsevier
Trypanosoma cruzi, the causative agent of Chagas disease, has at least two principal
intraspecific subdivisions, T. cruzi I (TCI) and T. cruzi II (TCII), the latter containing up to five …
intraspecific subdivisions, T. cruzi I (TCI) and T. cruzi II (TCII), the latter containing up to five …
Two Hybridization Events Define the Population Structure of Trypanosoma cruzi
SJ Westenberger, C Barnabé, DA Campbell… - Genetics, 2005 - academic.oup.com
Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and
pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T …
pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T …
Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications
A Herreros-Cabello, F Callejas-Hernández, N Gironès… - Genes, 2020 - mdpi.com
Chagas disease caused by the parasite Trypanosoma cruzi affects millions of people.
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
Although its first genome dates from 2005, its complexity hindered a complete assembly and …
Immunoregulatory networks in human C hagas disease
Chagas disease, caused by the infection with T rypanosoma cruzi, is endemic in all L atin A
merica. Due to the increase in population migration, C hagas disease has spread worldwide …
merica. Due to the increase in population migration, C hagas disease has spread worldwide …
Chagas disease diagnostic applications: present knowledge and future steps
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …
illness of major significance throughout Latin America and an emergent threat to global …