Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

[HTML][HTML] Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

Y Guo, H Bera, C Shi, L Zhang, D Cun… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Therapeutic application of peptides and proteins: parenteral forever?

Z Antosova, M Mackova, V Kral, T Macek - Trends in biotechnology, 2009 - cell.com
Varied therapeutic peptides and proteins represent a rapidly growing part of marketed drugs
and have an undisputed place alongside other established therapies. Nevertheless, such …

Orotransmucosal drug delivery systems: a review

NVS Madhav, AK Shakya, P Shakya, K Singh - Journal of controlled release, 2009 - Elsevier
Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers
several advantages over both injectable and enteral methods and also enhances drug …

[HTML][HTML] Pre-formulation and delivery strategies for the development of bacteriocins as next generation antibiotics

J Flynn, A Ryan, SP Hudson - European Journal of Pharmaceutics and …, 2021 - Elsevier
Bacteriocins, a class of antimicrobial peptide produced by bacteria, may offer a potential
alternative to traditional antibiotics, an important step towards mitigating the ever-increasing …

Peptide-based therapeutics: quality specifications, regulatory considerations, and prospects

S Rastogi, S Shukla, M Kalaivani, GN Singh - Drug discovery today, 2019 - Elsevier
Highlights•Harmonized pharmacopoeial peptide monograph will reduce manufacturer's
burden.•Quality assessment of peptides is crucial to ensure optimal safety to patients.•Purity …

Bile salt stabilized vesicles (bilosomes): a novel nano-pharmaceutical design for oral delivery of proteins and peptides

J Ahmad, M Singhal, S Amin… - Current …, 2017 - ingentaconnect.com
With the advent of novel vesicular drug delivery systems especially bilosomes, for large
molecular weight proteins and peptides, their oral administration seems a viable approach …

Palatal mucosa as a route for systemic drug delivery: A review

P Shakya, NVS Madhav, AK Shakya, K Singh - Journal of controlled release, 2011 - Elsevier
Rapid developments in the field of molecular biology and gene technology resulted in
generation of many macromolecular drugs including peptides, proteins, polysaccharides …

Review of recently used techniques and materials to improve the efficiency of orally administered proteins/peptides

YHEY Ibrahim, G Regdon, EI Hamedelniel… - DARU Journal of …, 2020 - Springer
Objectives The main objective of present review is to explore and evaluate the effectiveness
of recently developed methods to improve the bioavailability of orally administered …

Chitosan formulations as carriers for therapeutic proteins

F Andrade, F Antunes… - Current drug …, 2011 - ingentaconnect.com
Protein drugs represent a significant part of the new pharmaceuticals coming on the market
every year and are now widely spread in therapy to treat or relief symptomatology related to …