[HTML][HTML] Integrated modeling of biomarkers, survival and safety in clinical oncology drug development
Abstract Model-based approaches, including population pharmacokinetic-
pharmacodynamic modeling, have become an essential component in the clinical phases of …
pharmacodynamic modeling, have become an essential component in the clinical phases of …
Dose Titration of Ixazomib Maintenance Therapy in Transplant‐Ineligible Multiple Myeloma: Exposure–Response Analysis of the TOURMALINE‐MM4 Study
JK Srimani, PM Diderichsen, MJ Hanley… - Clinical …, 2023 - Wiley Online Library
Ixazomib has been approved in several countries as single‐agent maintenance therapy in
newly diagnosed multiple myeloma, in both posttransplant and transplant‐ineligible settings …
newly diagnosed multiple myeloma, in both posttransplant and transplant‐ineligible settings …
In silico trial for the assessment of givinostat dose adjustment rules based on the management of key hematological parameters in polycythemia vera patients
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by excessive
levels of platelets (PLT), white blood cells (WBC), and hematocrit (HCT). Givinostat …
levels of platelets (PLT), white blood cells (WBC), and hematocrit (HCT). Givinostat …
Proteasome inhibitor‐associated histiocytoid Sweet's syndrome: Clinical and histological similarities to Nakajo‐Nishimura syndrome suggest a potential mechanism
R Cho, S Nakajima, Y Kaku, J Tezuka… - The Journal of …, 2024 - Wiley Online Library
Histiocytoid Sweet's syndrome (HSS) is a variant of Sweet's syndrome (SS) that clinically
resembles SS but differs histologically by infiltrates, predominantly composed of immature …
resembles SS but differs histologically by infiltrates, predominantly composed of immature …
[PDF][PDF] Анализ фармакологических данных с использованием методов математического моделирования
ТА Яковлева - 2022 - impb.ru
Математическое моделирование представляет собой мощный инструмент для
анализа, позволяющий извлекать максимум полезной информации из данных и …
анализа, позволяющий извлекать максимум полезной информации из данных и …