Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Environmental enrichment improves learning and memory and long-term potentiation in young adult rats through a mechanism requiring mGluR5 signaling and …

R Hullinger, K O'Riordan, C Burger - Neurobiology of learning and memory, 2015 - Elsevier
Previous studies from our lab have demonstrated that mild cognitive impairments identified
early in life are predictive of cognitive deficits that develop with age, suggesting that …

Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity

GP Cortese, A Olin, K O'Riordan, R Hullinger… - Neurobiology of …, 2018 - Elsevier
Previous studies from our laboratory have shown that environmental enrichment (EE) in
young rats results in improved learning ability and enhanced metabotropic glutamate …

[HTML][HTML] Cognitive Impairment and Synaptic Dysfunction in Cardiovascular Disorders: The New Frontiers of the Heart–Brain Axis

T Soda, T Pasqua, G De Sarro, F Moccia - Biomedicines, 2024 - pmc.ncbi.nlm.nih.gov
Within the central nervous system, synaptic plasticity, fundamental to processes like learning
and memory, is largely driven by activity-dependent changes in synaptic strength. This …

The effects of hallucinogens on gene expression

DA Martin, CD Nichols - Behavioral neurobiology of psychedelic drugs, 2018 - Springer
The classic serotonergic hallucinogens, or psychedelics, have the ability to profoundly alter
perception and behavior. These can include visual distortions, hallucinations, detachment …

Molecular and cellular aspects of age-related cognitive decline and Alzheimer's disease

R Hullinger, L Puglielli - Behavioural brain research, 2017 - Elsevier
As the population of people aged 60 or older continues to rise, it has become increasingly
important to understand the molecular basis underlying age-related cognitive decline. In …

Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment

A Banerjee, JA Luong, A Ho, AO Saib, JE Ploski - Molecular autism, 2016 - Springer
Abstract Background Autism spectrum disorders (ASDs) represent a heterogeneous group
of disorders with a wide range of behavioral impairments including social and …

A review on the role of metabotropic glutamate receptors in neuroplasticity following psychostimulant use disorder

R Mozafari, S Karimi-Haghighi, M Fattahi… - Progress in Neuro …, 2023 - Elsevier
Abstract Psychostimulant Use Disorder (PUD) is a chronic relapsing disorder with high
motivation for drug abuse. In addition to develo** PUD, the use of psychostimulants is a …

Protein kinase C epsilon activity in the nucleus accumbens and central nucleus of the amygdala mediates binge alcohol consumption

DK Cozzoli, J Courson, C Rostock, RR Campbell… - Biological …, 2016 - Elsevier
Abstract background Protein kinase C epsilon (PKCε) is emerging as a potential target for
the development of pharmacotherapies to treat alcohol use disorders, yet little is known …