Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

Parkinson's disease (PD) is a complex neurodegenerative disorder with no cure in sight.
Clinical challenges of the disease include the inability to make a definitive diagnosis at the …

Parkinson's disease is a heterogeneous disorder with both motor and non-motor symptoms
that contribute to functional impairment. To develop effective, disease modifying treatments …

Brain iron deposition is a promising marker for human brain health, providing insightful
information for understanding aging as well as neurodegenerations, eg, Parkinson's disease …

Elevated levels of iron occur in both cortical and subcortical regions of the CNS in patients
with Alzheimer's disease. This accumulation is present early in the disease process as well …

Aging has been associated with iron retention in many cell types, including the neurons,
promoting neurodegeneration by ferroptosis. Excess intracellular iron accelerates aging by …

Objectives Iron deposition and mitochondrial dysfunction are closely associated with the
genesis and progression of Parkinson's disease (PD). This study aims to extract …

Parkinson's disease (PD) is a common neurodegenerative disorder. It has a delitescent
onset and a slow progress. The clinical manifestations of PD in patients are highly …

Objectives Brain iron deposition and microstructural changes in brain tissue are associated
with Parkinson's disease (PD). However, the correlation between these factors in …

In Parkinson's disease (PD), iron accumulation in the substantia nigra (SN) exacerbates
oxidative stress and α-synuclein aggregation, leading to neuronal death. However, the …