Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming develo** rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J **a - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

The potential of human peptide LL-37 as an antimicrobial and anti-biofilm agent

KE Ridyard, J Overhage - Antibiotics, 2021 - mdpi.com
The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

Antimicrobial peptides: mechanism of action, activity and clinical potential

QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …

A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …

Bioactive peptides: A promising alternative to chemical preservatives for food preservation

S Zhang, L Luo, X Sun, A Ma - Journal of Agricultural and Food …, 2021 - ACS Publications
Bioactive peptides used for food preservation can prolong the shelf life through
bacteriostasis and antioxidation. On the one hand, bioactive peptides can inhibit lipid …

[HTML][HTML] An update on antimicrobial peptides (AMPs) and their delivery strategies for wound infections

V Patrulea, G Borchard, O Jordan - Pharmaceutics, 2020 - mdpi.com
Bacterial infections occur when wound healing fails to reach the final stage of healing, which
is usually hindered by the presence of different pathogens. Different topical antimicrobial …

Incorporation of non-canonical amino acids into antimicrobial peptides: advances, challenges, and perspectives

Y Du, L Li, Y Zheng, J Liu, J Gong, Z Qiu… - Applied and …, 2022 - Am Soc Microbiol
The emergence of antimicrobial resistance is a global health concern and calls for the
development of novel antibiotic agents. Antimicrobial peptides seem to be promising …

Novel antimicrobial peptides modified with fluorinated sulfono-γ-AA having high stability and targeting multidrug-resistant bacteria infections

X Guo, X Miao, Y An, T Yan, Y Jia, B Deng, J Cai… - European Journal of …, 2024 - Elsevier
The emergence and increasing prevalence of multidrug-resistant (MDR) bacteria have
posed an urgent demand for novel antibacterial drugs. Currently, antimicrobial peptides …