Within the past ten years, a huge volume of research on the synthesis, structure-activity
relationships (SAR), and anticancer activities of the urea derivatives was reported. Many …

This study aims to investigate the protective effects of gastrodin (GSTD), a natural compound
isolated from the root of Gastrodia elata BL., on ethanol-induced liver injury and apoptosis in …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
throughout the world. Although hepatitis B or C viral infections are main risk factors for HCC …

Aberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant
mammary epithelial cells are strongly associated with the progression of breast cancer …

The mangiferin‐berberine (MB) salt was synthesized by ionic bonding of mangiferin (M) and
berberine (B) at an equal molecular ratio. This study aimed to investigate the activities of MB …

Purpose: We have synthesized a new tubulin ligand N-(2, 6-dimethoxypyridine-3-yl)-9-
methylcarbazole-3-sulfonamide (IG-105). This work investigates its anticancer effect and …

We have discovered several tubulin-active compounds in our previous studies. In the
establishment of a compound library of small molecule weight tubulin ligands, 14 new N-3 …

Abstract GMC-5-193 (GMC) is a novel anticancer small-molecule quinazolinone analogue
with properties that include antimicrotubule activity and inherent fluorescence. The aim of …

Anti-microtubule drugs that cause mitotic arrest and subsequent apoptosis of cancer cells
are frequently used to treat breast cancer patients with advanced or metastatic diseases …

Forty-six new compounds were synthesized on the basis of our knowledge of the 3-
haloacylamino benzoylurea (HBU) series. Structure− activity relationship (SAR) analysis …