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Glucocorticoids, genes and brain function
GR Juszczak, AM Stankiewicz - Progress in Neuro-Psychopharmacology …, 2018 - Elsevier
The identification of key genes in transcriptomic data constitutes a huge challenge. Our
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
review of microarray reports revealed 88 genes whose transcription is consistently regulated …
Calcium permeable channels in cancer hallmarks
Cancer, the second cause of death worldwide, is characterized by several common criteria,
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring autophagy 1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah… - …, 2021 - pmc.ncbi.nlm.nih.gov
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations
Across biological systems, cells undergo coordinated changes in gene expression, resulting
in transcriptome dynamics that unfold within a low-dimensional manifold. While low …
in transcriptome dynamics that unfold within a low-dimensional manifold. While low …
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle
Inbred animals were historically chosen for genome analysis to circumvent assembly issues
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
Calmodulin mutations in human disease
ABSTRACT Calcium ions (Ca2+) are the basis of a unique and potent array of cellular
responses. Calmodulin (CaM) is a small but vital protein that is able to rapidly transmit …
responses. Calmodulin (CaM) is a small but vital protein that is able to rapidly transmit …
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
N Alphonse, JJ Wanford, AA Voak, J Gay, S Venkhaya… - Cell, 2022 - cell.com
Interferons (IFNs) induce an antimicrobial state, protecting tissues from infection. Many
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …
viruses inhibit IFN signaling, but whether bacterial pathogens evade IFN responses remains …
Oncogenic Ras isoforms signaling specificity at the membrane
How do Ras isoforms attain oncogenic specificity at the membrane? Oncogenic KRas,
HRas, and NRas (K-Ras, H-Ras, and N-Ras) differentially populate distinct cancers. How …
HRas, and NRas (K-Ras, H-Ras, and N-Ras) differentially populate distinct cancers. How …
The role of calmodulin in tumor cell migration, invasiveness, and metastasis
Calmodulin (CaM) is the principal Ca2+ sensor protein in all eukaryotic cells, that upon
binding to target proteins transduces signals encoded by global or subcellular-specific …
binding to target proteins transduces signals encoded by global or subcellular-specific …