Environmental toxicity, oxidative stress and apoptosis: menage a trois

R Franco, R Sánchez-Olea, EM Reyes-Reyes… - … /Genetic Toxicology and …, 2009 - Elsevier
Apoptosis is an evolutionary conserved homeostatic process involved in distinct
physiological processes including organ and tissue morphogenesis, development and …

[HTML][HTML] Study on the mechanism of liver toxicity induced by acenaphthene in zebrafish

J Zhang, K Wang, J Guo, Y Huang, Y Wei, K Jia… - Ecotoxicology and …, 2023 - Elsevier
Acenaphthene is a polycyclic aromatic hydrocarbon (PAH) that is a widely distributed
environmental pollutant that accumulates in organisms and leads to health risks in humans …

Apoptosis and blood-testis barrier disruption during male reproductive dysfunction induced by PAHs of different molecular weights

L Zhang, X Ji, F Ding, X Wu, N Tang, Q Wu - Environmental Pollution, 2022 - Elsevier
The association between polycyclic aromatic hydrocarbons (PAHs) and male reproductive
dysfunction has attracted increasing attention. The purpose of this study was to compare the …

Joint effect of polycyclic aromatic hydrocarbons and phthalates exposure on telomere length and lung function

J Hou, W Yin, P Li, C Hu, T Xu, J Cheng, T Li… - Journal of Hazardous …, 2020 - Elsevier
Exposure to polycyclic aromatic hydrocarbons and phthalates are linked to lung function
decline and altered relative telomere length (RTL) accompanying with oxidative stress and …

Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of …

Z Andrysík, J Vondráček, S Marvanová… - Mutation Research …, 2011 - Elsevier
Many of the toxic and carcinogenic effects of urban air pollution have been linked to
polycyclic aromatic hydrocarbons (PAHs) adsorbed to airborne particulate matter (PM). The …

Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats

V Kummer, J Mašková, Z Zralý, J Neča, P Šimečková… - Toxicology letters, 2008 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are an important group of environmental
pollutants, known for their mutagenic and carcinogenic activities. Many PAHs are aryl …

Benzo [a] pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells

G Vázquez-Gómez, L Rocha-Zavaleta… - Toxicology letters, 2018 - Elsevier
Abstract Benzo [a] pyrene (B [a] P), the most extensively studied carcinogen in cigarette
smoke, has been regarded as a critical mediator of lung cancer. It is known that B [a] P …

Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway

L Šmerdová, J Svobodová, M Kabátková… - …, 2014 - academic.oup.com
Abstract Cytochrome P450 1B1 (CYP1B1) is an enzyme that has a unique tumor-specific
pattern of expression and is capable of bioactivating a wide range of carcinogenic …

Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in Czech river sediments and their effects on toxic events associated with …

J Vondráĉek, L Ŝvihálková‐Ŝindlerová… - … and Chemistry: An …, 2007 - Wiley Online Library
Alkylated polycyclic aromatic hydrocarbons (PAHs) are important environmental pollutants.
In the present study, we determined levels of monomethylated naphthalenes (MeNap) …

An in vitro cytotoxicities comparison of 16 priority polycyclic aromatic hydrocarbons in human pulmonary alveolar epithelial cells HPAEpiC

S Ke, Q Liu, Y Yao, X Zhang, G Sui - Toxicology letters, 2018 - Elsevier
In present study, we compared for the first time the cytotoxicities of the 16 priority polycyclic
aromatic hydrocarbons (PAHs) in human pulmonary alveolar epithelial cells HPAEpiC …