An escape from ESKAPE pathogens: A comprehensive review on current and emerging therapeutics against antibiotic resistance

A Singh, M Tanwar, TP Singh, S Sharma… - International Journal of …, 2024 - Elsevier
The rise of antimicrobial resistance has positioned ESKAPE pathogens as a serious global
health threat, primarily due to the limitations and frequent failures of current treatment …

[HTML][HTML] Drug–Drug Interactions in Nosocomial Infections: An Updated Review for Clinicians

S Hîncu, MM Apetroaei, G Ștefan, AI Fâcă, AL Arsene… - Pharmaceutics, 2024 - mdpi.com
Prevention, assessment, and identification of drug–drug interactions (DDIs) represent a
challenge for healthcare professionals, especially in nosocomial settings. This narrative …

Bioenergetic suppression by redox-active metabolites promotes antibiotic tolerance in Pseudomonas aeruginosa

RD Horak, JA Ciemniecki, DK Newman - Proceedings of the National …, 2024 - pnas.org
The proton-motive force (PMF), consisting of a pH gradient and a membrane potential (ΔΨ)
underpins many processes essential to bacterial growth and/or survival. Yet bacteria often …

Understanding the evolution and transmission dynamics of antibiotic resistance genes: a comprehensive review

AKMZ Hossain… - Journal of Basic …, 2024 - Wiley Online Library
Antibiotic resistance poses a formidable challenge to global public health, necessitating
comprehensive understanding and strategic interventions. This review explores the …

Molecular determinant deciphering of MIC-guided RND efflux substrates in E. coli

J Revol-Tissot, G Boyer, S Alibert - Frontiers in Drug Discovery, 2024 - frontiersin.org
Antimicrobial resistance poses an urgent and formidable global public health threat. The
escalation of bacterial multidrug resistance to antibiotics has the potential to become a …

Potential Risks and Challenges of Bacterial Persistence in Food Safety

J Dawan, J Kim, X Liao, T Ding… - Food Reviews International, 2025 - Taylor & Francis
Bacterial persisters are becoming increasingly recognized as an emerging public health
concern due to the potential causes of chronic infections in clinical settings and treatment …

Inactivation of the ribosome assembly factor RimP causes streptomycin resistance and impairs motility in Salmonella

Z Lyu, Y Ling, A van Hoof, J Ling - Antimicrobial Agents and …, 2024 - Am Soc Microbiol
The ribosome is the central hub for protein synthesis and the target of many antibiotics.
Although the majority of ribosome-targeting antibiotics inhibit protein synthesis and are …

Anthrapyrazolone functionalized Oligo (ethylene glycol) methyl ether methacrylates based fluorescent polymeric hydrogel for selective detection of Tetracycline drug

G Sivakumar, A Babu, M Anandhan, V Nutalapati… - European Polymer …, 2024 - Elsevier
Tetracycline (TC) antibiotics are essential for treating bacterial infections; however, overuse
and improper disposal place the environment in danger and promote the growth of drug …

A Cell-Based Screening Assay for rRNA-Targeted Drug Discovery

S Story, DP Arya - ACS Infectious Diseases, 2024 - ACS Publications
Worldwide, bacterial antibiotic resistance continues to outpace the level of drug
development. One way to counteract this threat to society is to identify novel ways to rapidly …

[HTML][HTML] Genetic variations underlying aminoglycoside resistance in antibiotic-induced Mycobacterium intracellulare mutants

HE Park, JI Shin, KM Kim, JG Choi, WJ Anh… - Infection, Genetics and …, 2025 - Elsevier
Mycobacterium avium complex (MAC) is an emerging pathogen leading to public health
concerns in develo** and developed countries, particularly among immunocompromised …