Environment-benign, multicomponent synthetic methodologies are vital in modern
pharmaceutical research and facilitates multi-targeted drug development via synergistic …

Thiazolidinedione derivatives represent nitrogen‐containing heterocyclic compounds
utilized in type 2 diabetes mellitus management. Recent advances in medicinal chemistry …

This study explores the capability of thiazoles as potent inhibitors of SARS‐CoV‐2 Mpro.
Seventeen thiazoles (1–17) were screened for their linking affinity with the active site of …

Deep eutectic solvents (DES) are environmentally friendly solvents that prevent the use of
toxic organic solvents and have been extensively studied in recent years. However, volatile …

A transition-metal free methodology for the chemoselective reduction of benzylidene
thiazolidine-2, 4-diones and similar heterocycles is described, allowing the preparation of a …

In this paper, we attempted to develop a novel class of compounds against lipoxygenase, a
key enzyme in the biosynthesis of leukotrienes implicated in a series of inflammatory …

The Knoevenagel condensation is a powerful and primary step for the development of
carbon-carbon bond transformations. These condensations offer versatile …

Objective: A newer series of compounds, including 3-benzoyl-5-(substituted-benzylidin)-
thiazolidin-2, 4-dione (IVa–IVh) and 3-p-tolyl-5-(substituted-benzylidine)-thiazolidin-2, 4 …

A simple and rapid procedure is developed for the synthesis of 5-arylidene-thiazolidine-2, 4-
dione derivatives by the Knoevenagel reaction between a variety of aromatic aldehydes and …

Organoselenocyanates are important classes of organoselenium compounds having
potential pharmaceutical applications in cancer biology. In the present study, two different …