Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Kléber, André G., and Yoram Rudy. Basic Mechanisms of Cardiac Impulse Propagation and
Associated Arrhythmias. Physiol Rev 84: 431–488, 2004; 10.1152/physrev. 00025.2003 …

The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via
mechanical and electrical junctions. Although described in some detail by light microscopy …

Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Adjacent cells share ions, second messengers and small metabotes through intercellular
channels which are present in gap junctions. This type of intercellular communication …

Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …

The aim of this review is to provide basic information on the electrophysiological changes
during acute ischemia and reperfusion from the level of ion channels up to the level of …

Gap junctions are specialized membrane domains composed of collections of channels that
directly connect neighboring cells providing for the cell-to-cell diffusion of small molecules …

Pannexin 1 (PANX1) channels mediate release of ATP, a" find-me" signal that recruits
macrophages to apoptotic cells; PANX1 activation during apoptosis requires caspase …