Muscle glycogen metabolism and high-intensity exercise performance: a narrative review
Muscle glycogen is the main substrate during high-intensity exercise and large reductions
can occur after relatively short durations. Moreover, muscle glycogen is stored …
can occur after relatively short durations. Moreover, muscle glycogen is stored …
The structural basis of ryanodine receptor ion channel function
G Meissner - Journal of General Physiology, 2017 - rupress.org
Large-conductance Ca2+ release channels known as ryanodine receptors (RyRs) mediate
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …
Structural basis for gating and activation of RyR1
The type-1 ryanodine receptor (RyR1) is an intracellular calcium (Ca 2+) release channel
required for skeletal muscle contraction. Here, we present cryo-EM reconstructions of RyR1 …
required for skeletal muscle contraction. Here, we present cryo-EM reconstructions of RyR1 …
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment
Ryanodine receptor type 2 (RyR2) mutations have been linked to an inherited form of
exercise-induced sudden cardiac death called catecholaminergic polymorphic ventricular …
exercise-induced sudden cardiac death called catecholaminergic polymorphic ventricular …
Review of RyR1 pathway and associated pathomechanisms
JW Witherspoon, KG Meilleur - Acta neuropathologica communications, 2016 - Springer
Abstract Ryanodine receptor isoform-1 (RyR1) is a major calcium channel in skeletal muscle
important for excitation-contraction coupling. Mutations in the RYR1 gene yield RyR1 protein …
important for excitation-contraction coupling. Mutations in the RYR1 gene yield RyR1 protein …
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation
The type 1 ryanodine receptor (RyR1) is an intracellular calcium (Ca 2+) release channel on
the sarcoplasmic/endoplasmic reticulum that is required for skeletal muscle contraction …
the sarcoplasmic/endoplasmic reticulum that is required for skeletal muscle contraction …
Age‐related changes in mitochondrial function of mouse colonic smooth muscle: beneficial effects of melatonin
FE Martin‐Cano, C Camello‐Almaraz… - Journal of pineal …, 2014 - Wiley Online Library
Aging is a multifactorial process that involves biochemical, structural, and functional
changes in mitochondria. The ability of melatonin to palliate the alterations induced by aging …
changes in mitochondria. The ability of melatonin to palliate the alterations induced by aging …
Comparative Proteomics Analyses of Pollination Response in Endangered Orchid Species Dendrobium Chrysanthum
W Wang, H Yu, T Li, L Li, G Zhang, Z Liu… - International Journal of …, 2017 - mdpi.com
Pollination is a crucial stage in plant reproductive process. The self-compatibility (SC) and
self-incompatibility (SI) mechanisms determined the plant genetic diversity and species …
self-incompatibility (SI) mechanisms determined the plant genetic diversity and species …
Potassium dependent rescue of a myopathy with core-like structures in mouse
MG Hanson, JJ Wilde, RL Moreno, AD Minic… - Elife, 2015 - elifesciences.org
Myopathies decrease muscle functionality. Mutations in ryanodine receptor 1 (RyR1) are
often associated with myopathies with microscopic core-like structures in the muscle fiber. In …
often associated with myopathies with microscopic core-like structures in the muscle fiber. In …
ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor
Background This study was designed to determine whether the cardiac ryanodine receptor
(RyR2) central domain, a region associated with catecholamine polymorphic ventricular …
(RyR2) central domain, a region associated with catecholamine polymorphic ventricular …