Light sheet fluorescence microscopy

EHK Stelzer, F Strobl, BJ Chang, F Preusser… - Nature Reviews …, 2021 - nature.com
Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

The difficulty of computing stable and accurate neural networks: On the barriers of deep learning and Smale's 18th problem

MJ Colbrook, V Antun… - Proceedings of the …, 2022 - National Acad Sciences
Deep learning (DL) has had unprecedented success and is now entering scientific
computing with full force. However, current DL methods typically suffer from instability, even …

Avoiding a replication crisis in deep-learning-based bioimage analysis

RF Laine, I Arganda-Carreras, R Henriques… - Nature …, 2021 - nature.com
Deep learning algorithms are powerful tools for analyzing, restoring and transforming
bioimaging data. One promise of deep learning is parameter-free one-click image analysis …

Removing independent noise in systems neuroscience data using DeepInterpolation

J Lecoq, M Oliver, JH Siegle, N Orlova… - Nature …, 2021 - nature.com
Progress in many scientific disciplines is hindered by the presence of independent noise.
Technologies for measuring neural activity (calcium imaging, extracellular electrophysiology …

Self-supervised deep learning for tracking degradation of perovskite light-emitting diodes with multispectral imaging

K Ji, W Lin, Y Sun, LS Cui, J Shamsi… - Nature Machine …, 2023 - nature.com
Emerging functional materials such as halide perovskites are intrinsically unstable, causing
long-term instability in optoelectronic devices made from these materials. This leads to …

Structured illumination microscopy with noise-controlled image reconstructions

CS Smith, JA Slotman, L Schermelleh, N Chakrova… - Nature …, 2021 - nature.com
Super-resolution structured illumination microscopy (SIM) has become a widely used
method for biological imaging. Standard reconstruction algorithms, however, are prone to …

Deep learning-enhanced light-field imaging with continuous validation

N Wagner, F Beuttenmueller, N Norlin, J Gierten… - Nature …, 2021 - nature.com
Visualizing dynamic processes over large, three-dimensional fields of view at high speed is
essential for many applications in the life sciences. Light-field microscopy (LFM) has …

A versatile Wavelet-Enhanced CNN-Transformer for improved fluorescence microscopy image restoration

Q Wang, Z Li, S Zhang, N Chi, Q Dai - Neural Networks, 2024 - Elsevier
Fluorescence microscopes are indispensable tools for the life science research community.
Nevertheless, the presence of optical component limitations, coupled with the maximum …