Toward explainable artificial intelligence for precision pathology

F Klauschen, J Dippel, P Keyl… - Annual Review of …, 2024‏ - annualreviews.org
The rapid development of precision medicine in recent years has started to challenge
diagnostic pathology with respect to its ability to analyze histological images and …

Deep learning in cancer diagnosis, prognosis and treatment selection

KA Tran, O Kondrashova, A Bradley, ED Williams… - Genome medicine, 2021‏ - Springer
Deep learning is a subdiscipline of artificial intelligence that uses a machine learning
technique called artificial neural networks to extract patterns and make predictions from …

[HTML][HTML] Explainable artificial intelligence (XAI) in deep learning-based medical image analysis

BHM Van der Velden, HJ Kuijf, KGA Gilhuijs… - Medical Image …, 2022‏ - Elsevier
With an increase in deep learning-based methods, the call for explainability of such methods
grows, especially in high-stakes decision making areas such as medical image analysis …

Explaining deep neural networks and beyond: A review of methods and applications

W Samek, G Montavon, S Lapuschkin… - Proceedings of the …, 2021‏ - ieeexplore.ieee.org
With the broader and highly successful usage of machine learning (ML) in industry and the
sciences, there has been a growing demand for explainable artificial intelligence (XAI) …

Dermatologist-like explainable AI enhances trust and confidence in diagnosing melanoma

T Chanda, K Hauser, S Hobelsberger… - Nature …, 2024‏ - nature.com
Artificial intelligence (AI) systems have been shown to help dermatologists diagnose
melanoma more accurately, however they lack transparency, hindering user acceptance …

[HTML][HTML] Explainable artificial intelligence in skin cancer recognition: A systematic review

K Hauser, A Kurz, S Haggenmüller, RC Maron… - European Journal of …, 2022‏ - Elsevier
Background Due to their ability to solve complex problems, deep neural networks (DNNs)
are becoming increasingly popular in medical applications. However, decision-making by …

[HTML][HTML] Pruning by explaining: A novel criterion for deep neural network pruning

SK Yeom, P Seegerer, S Lapuschkin, A Binder… - Pattern Recognition, 2021‏ - Elsevier
The success of convolutional neural networks (CNNs) in various applications is
accompanied by a significant increase in computation and parameter storage costs. Recent …

[HTML][HTML] Hierarchical graph representations in digital pathology

P Pati, G Jaume, A Foncubierta-Rodriguez… - Medical image …, 2022‏ - Elsevier
Cancer diagnosis, prognosis, and therapy response predictions from tissue specimens
highly depend on the phenotype and topological distribution of constituting histological …

Towards best practice in explaining neural network decisions with LRP

M Kohlbrenner, A Bauer, S Nakajima… - … Joint Conference on …, 2020‏ - ieeexplore.ieee.org
Within the last decade, neural network based predictors have demonstrated impressive-and
at times superhuman-capabilities. This performance is often paid for with an intransparent …

A generalized deep learning framework for whole-slide image segmentation and analysis

M Khened, A Kori, H Rajkumar, G Krishnamurthi… - Scientific reports, 2021‏ - nature.com
Histopathology tissue analysis is considered the gold standard in cancer diagnosis and
prognosis. Whole-slide imaging (WSI), ie, the scanning and digitization of entire histology …