Idiopathic pulmonary fibrosis and lung cancer: mechanisms and molecular targets

B Ballester, J Milara, J Cortijo - International journal of molecular sciences, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …

Thy‐1 as a regulator of cell‐cell and cell‐matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis

TA Rege, JS Hagood - The FASEB journal, 2006 - Wiley Online Library
ABSTRACT Thy‐1 (CD90) is a 25–37 kDa glyco‐sylphosphatidylinositol (GPI)‐anchored
glycoprotein expressed on many cell types, including T cells, thymocytes, neurons …

Stanniocalcin 1 promotes metastasis, lipid metabolism and cisplatin chemoresistance via the FOXC2/ITGB6 signaling axis in ovarian cancer

F Lin, X Li, X Wang, H Sun, Z Wang, X Wang - Journal of Experimental & …, 2022 - Springer
Abstract Background Stanniocalcin 1 (STC1) plays an integral role in ovarian cancer (OC).
However, the functional role of STC1 in metastasis, lipid metabolism and cisplatin (DDP) …

Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance

M Lin, XL Zhang, R You, YP Liu, HM Cai, LZ Liu… - Nature …, 2023 - nature.com
It is critical to understand factors associated with nasopharyngeal carcinoma (NPC)
metastasis. To track the evolutionary route of metastasis, here we perform an integrative …

A reduction in CD90 (THY-1) expression results in increased differentiation of mesenchymal stromal cells

DA Moraes, TT Sibov, LF Pavon, PQ Alvim… - Stem cell research & …, 2016 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) are multipotent progenitor cells
used in several cell therapies. MSCs are characterized by the expression of CD73, CD90 …

CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer

L Zhang, Q Zhou, Q Qiu, L Hou, M Wu, J Li, X Li, B Lu… - Molecular Cancer, 2019 - Springer
Background Emerging evidence has shown that circular RNAs (circRNAs) play essential
roles in cancer biology and are potential biomarkers and targets for cancer therapy …

MicroRNAs in idiopathic pulmonary fibrosis

KV Pandit, J Milosevic, N Kaminski - Translational research, 2011 - Elsevier
In this review, we describe the recent advances in the understanding of the role of
microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and lethal fibrotic …

Altered DNA methylation profile in idiopathic pulmonary fibrosis

YY Sanders, N Ambalavanan, B Halloran… - American journal of …, 2012 - atsjournals.org
Rationale: DNA methylation is an important epigenetic mechanism, which often occurs in
response to environmental stimuli and is crucial in regulating gene expression. It is likely …

Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments

Q Tao, ATC Chan - Expert reviews in molecular medicine, 2007 - cambridge.org
Nasopharyngeal carcinoma (NPC) is a prevalent tumour in southern China and southeast
Asia, particularly in the Cantonese population, where its incidence has remained high for …

Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approaches

KW Lo, GTY Chung, KF To - Seminars in cancer biology, 2012 - Elsevier
Nasopharyngeal carcinoma (NPC) is consistently associated with EBV infection and
prevalence in southern China and Southeast Asia. In addition to EBV, the development of …