Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

Continuous twin screw wet granulation is one of the key continuous manufacturing
technologies that have gained significant interest in the pharmaceutical industry as well as …

Since the Handbook of Pharmaceutical Granulation Technology, first and second editions,
were published, there have been rapid developments in the science of granulation, particle …

In this paper, a compression behavior classification system (CBCS) for direct compression
(DC) pharmaceutical powders is presented. Seven descriptors from a series of compression …

Understanding the surface properties of particles is crucial for optimizing the performance of
formulated products in various industries. However, acquiring this understanding often …

We propose a generalization of the Weibull dissolution model, referred to as generalized
Weibull dissolution model, that seamlessly captures all three fractional dissolution rates …

The MCS initiative was first introduced in 2013. Since then, two MCS papers have been
published: the first proposing a structured approach to consider the impact of drug …

The present study used polymers such as PLA and ABS filaments for the 3D printing parts
with varying layer thicknesses. The mechanical properties and surface finish of the as …

Pharmaceutical products represent a meaningful target for sustainability improvement and
emissions reduction. It is proposed here that rethinking the standard, and often linear …

By means of a science and risk-based systematic approach to pharmaceutical product
development through the DoE/QbD system, a control strategy will be defined for each of the …