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[PDF][PDF] Protective alleles and precision healthcare in crewed spaceflight
Common and rare alleles are now being annotated across millions of human genomes, and
omics technologies are increasingly being used to develop health and treatment …
omics technologies are increasingly being used to develop health and treatment …
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA)
Abstract The SpaceX Inspiration4 mission provided a unique opportunity to study the impact
of spaceflight on the human body. Biospecimen samples were collected from four crew …
of spaceflight on the human body. Biospecimen samples were collected from four crew …
Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing
Telomeres are repetitive nucleoprotein complexes at chromosomal termini essential for
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …
Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses
The advent of civilian spaceflight challenges scientists to precisely describe the effects of
spaceflight on human physiology, particularly at the molecular and cellular level. Newer …
spaceflight on human physiology, particularly at the molecular and cellular level. Newer …
NASA open science data repository: open science for life in space
SG Gebre, RT Scott, AM Saravia-Butler… - Nucleic Acids …, 2025 - academic.oup.com
Abstract Space biology and health data are critical for the success of deep space missions
and sustainable human presence off-world. At the core of effectively managing biomedical …
and sustainable human presence off-world. At the core of effectively managing biomedical …
To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants
In the era of renewed space exploration, comprehending the effects of the space
environment on human health, particularly for deep space missions, is crucial. While …
environment on human health, particularly for deep space missions, is crucial. While …
Biological horizons: pioneering open science in the cosmos
SV Costes, CL Gentemann, SH Platts… - Nature …, 2024 - nature.com
With precious few spaceflight missions, all space-related biological and biomedical-health
data are priceless national resources that anyone should be able to easily access. The …
data are priceless national resources that anyone should be able to easily access. The …
Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts' blood cells in space
M Moreno-Villanueva, LE Jimenez-Chavez… - Frontiers in …, 2025 - frontiersin.org
Introduction The impact of spaceflight on the immune system and mitochondria has been
investigated for decades. However, the molecular mechanisms underlying spaceflight …
investigated for decades. However, the molecular mechanisms underlying spaceflight …
Aging and putative frailty biomarkers are altered by spaceflight
Human space exploration poses inherent risks to astronauts' health, leading to molecular
changes that can significantly impact their well-being. These alterations encompass …
changes that can significantly impact their well-being. These alterations encompass …
Advancing space medicine: a global perspective on in-orbit research and future directions
SG Chen, XP Chen, B Wu - Military Medical Research, 2025 - Springer
As humanity ventures deeper into space, our challenges become increasingly complex.
Space medicine, once confined to ensuring the health and safety of astronauts on low-Earth …
Space medicine, once confined to ensuring the health and safety of astronauts on low-Earth …