Nanotechnology in combating biofilm: A smart and promising therapeutic strategy

YK Mohanta, I Chakrabartty, AK Mishra… - Frontiers in …, 2023‏ - frontiersin.org
Since the birth of civilization, people have recognized that infectious microbes cause serious
and often fatal diseases in humans. One of the most dangerous characteristics of …

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era

M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013‏ - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013‏ - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

A brief history of the antibiotic era: lessons learned and challenges for the future

RI Aminov - Frontiers in microbiology, 2010‏ - frontiersin.org
This article gives a very brief overview of the antibiotic era, beginning from the discovery of
first antibiotics until the present day situation, which is marred by the emergence of hard-to …

AI-2-mediated signalling in bacteria

CS Pereira, JA Thompson… - FEMS microbiology …, 2013‏ - academic.oup.com
Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Acyl-homoserine lactone-based quorum sensing and quorum quenching hold promise to determine the performance of biological wastewater treatments: an overview

J Huang, Y Shi, G Zeng, Y Gu, G Chen, L Shi, Y Hu… - Chemosphere, 2016‏ - Elsevier
Quorum sensing (QS) is a communication process between cells, in which bacteria secrete
and sense the specific chemicals, and regulate gene expression in response to population …

A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013‏ - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials

KMG O'Connell, JT Hodgkinson… - Angewandte Chemie …, 2013‏ - Wiley Online Library
The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th
century completely revolutionized clinical practices and helped to facilitate the development …

Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity

M Starkey, F Lepine, D Maura… - PLoS …, 2014‏ - journals.plos.org
Etiological agents of acute, persistent, or relapsing clinical infections are often refractory to
antibiotics due to multidrug resistance and/or antibiotic tolerance. Pseudomonas aeruginosa …

Monitoring bacterial twitter: does quorum sensing determine the behavior of water and wastewater treatment biofilms?

JD Shrout, R Nerenberg - Environmental science & technology, 2012‏ - ACS Publications
Bacteria have their own form of “twitter” communication, described as quorum sensing (QS),
where bacteria emit and sense chemical signal molecules as a means to gauge population …