[HTML][HTML] Experience and new prospects of PET imaging for ion beam therapy monitoring

K Parodi, T Yamaya, P Moskal - Zeitschrift für Medizinische Physik, 2023 - Elsevier
Pioneering investigations on the usage of positron-emission-tomography (PET) for the
monitoring of ion beam therapy with light (protons, helium) and heavier (stable and …

Management of motion and anatomical variations in charged particle therapy: past, present, and into the future

JM Pakela, A Knopf, L Dong, A Rucinski… - Frontiers in …, 2022 - frontiersin.org
The major aim of radiation therapy is to provide curative or palliative treatment to cancerous
malignancies while minimizing damage to healthy tissues. Charged particle radiotherapy …

Proton therapy monitoring: spatiotemporal emission reconstruction with prompt gamma timing and implementation with PET detectors

F Pennazio, V Ferrero, G D'Onghia… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. In this study we introduce spatiotemporal emission reconstruction prompt gamma
timing (SER-PGT), a new method to directly reconstruct the prompt photon emission in the …

[HTML][HTML] Hadron therapy achievements and challenges: The CNAO experience

S Rossi - Physics, 2022 - mdpi.com
Protons and carbon ions (hadrons) have useful properties for the treatments of patients
affected by oncological pathologies. They are more precise than conventional X-rays and …

Detection of Interfractional Morphological Changes in Proton Therapy: A Simulation and In Vivo Study With the INSIDE In-Beam PET

E Fiorina, V Ferrero, G Baroni, G Battistoni… - Frontiers in …, 2021 - frontiersin.org
In particle therapy, the uncertainty of the delivered particle range during the patient
irradiation limits the optimization of the treatment planning. Therefore, an in vivo treatment …

In-beam PET treatment monitoring of carbon therapy patients: Results of a clinical trial at CNAO

AC Kraan, F Susini, M Moglioni, G Battistoni, D Bersani… - Physica Medica, 2024 - Elsevier
Purpose: Carbon ion therapy treatments can be monitored non-invasively with in-beam
Positron Emission Tomography (PET). At CNAO the INSIDE in-beam PET scanner has been …

[HTML][HTML] Prompt-gamma fall-off estimation with C-ion irradiation at clinical energies, using a knife-edge slit camera: A Monte Carlo study

A Missaglia, A Bourkadi-Idrissi, F Casamichiela… - Physica medica, 2023 - Elsevier
Purpose: In-vivo range verification has been a hot topic in particle therapy since two
decades. Many efforts have been done for proton therapy, while fewer studies were …

Inhomogeneity detection within a head-sized phantom using tracking of charged nuclear fragments in ion beam therapy

R Félix-Bautista, L Ghesquière-Diérickx… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. The highly conformal carbon-ion radiotherapy is associated with an increased
sensitivity of the dose distributions to internal changes in the patient during the treatment …

Monitoring carbon ion beams transverse position detecting charged secondary fragments: Results from patient treatment performed at CNAO

M Toppi, G Baroni, G Battistoni, MG Bisogni… - Frontiers in …, 2021 - frontiersin.org
Particle therapy in which deep seated tumours are treated using 12C ions (Carbon Ions
RadioTherapy or CIRT) exploits the high conformity in the dose release, the high relative …

First experimental verification of prompt gamma imaging with carbon ion irradiation

AB Idrissi, G Borghi, A Caracciolo, C Riboldi… - Scientific Reports, 2024 - nature.com
Abstract Prompt Gamma Imaging (PGI) is a promising technique for range verification in
Particle Therapy. This technique was already tested in clinical environment with a knife …