Dilated cardiomyopathy and chronic cardiac inflammation: Pathogenesis, diagnosis and therapy
D Harding, MHA Chong, N Lahoti… - Journal of internal …, 2023 - Wiley Online Library
Dilated cardiomyopathy (DCM) is typically defined by left ventricular dilation and systolic
dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of …
dysfunction in the absence of a clear precipitant. Idiopathic disease is common; up to 50% of …
The quest for new approaches in myocarditis and inflammatory cardiomyopathy
S Heymans, U Eriksson, J Lehtonen… - Journal of the American …, 2016 - jacc.org
Myocarditis is a diverse group of heart-specific immune processes classified by clinical and
histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with …
histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with …
IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation
A Amorim, D De Feo, E Friebel, F Ingelfinger… - Nature …, 2022 - nature.com
Abstract During inflammation, Ly6Chi monocytes are rapidly mobilized from the bone
marrow (BM) and are recruited into inflamed tissues, where they undergo monocyte-to …
marrow (BM) and are recruited into inflamed tissues, where they undergo monocyte-to …
Cardiac autoimmunity: myocarditis
W Bracamonte-Baran, D Čiháková - The immunology of cardiovascular …, 2017 - Springer
Myocarditis is the inflammation of the muscle tissues of the heart (myocardium). After a
pathologic cardiac-specific inflammatory process, it may progress to chronic damage and …
pathologic cardiac-specific inflammatory process, it may progress to chronic damage and …
An overview of the immune mechanisms of viral myocarditis
N Lasrado, J Reddy - Reviews in medical virology, 2020 - Wiley Online Library
Viral myocarditis has been identified as a major cause of dilated cardiomyopathy (DCM) that
can lead to heart failure. Historically, Coxsackieviruses and adenoviruses have been …
can lead to heart failure. Historically, Coxsackieviruses and adenoviruses have been …
Myocarditis in humans and in experimental animal models
P Błyszczuk - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Myocarditis is defined as an inflammation of the cardiac muscle. In humans, various
infectious and non-infectious triggers induce myocarditis with a broad spectrum of …
infectious and non-infectious triggers induce myocarditis with a broad spectrum of …
Cardiac myosin-Th17 responses promote heart failure in human myocarditis
JM Myers, LT Cooper, DC Kem, S Stavrakis… - JCI …, 2016 - pmc.ncbi.nlm.nih.gov
In human myocarditis and its sequela dilated cardiomyopathy (DCM), the mechanisms and
immune phenotype governing disease and subsequent heart failure are not known. Here …
immune phenotype governing disease and subsequent heart failure are not known. Here …
Eosinophils in autoimmune diseases
NL Diny, NR Rose, D Čiháková - Frontiers in immunology, 2017 - frontiersin.org
Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of
inflammation. Their role in asthma and parasitic infections has long been recognized …
inflammation. Their role in asthma and parasitic infections has long been recognized …
Viral myocarditis
NR Rose - Current opinion in rheumatology, 2016 - journals.lww.com
Treatment of myocarditis is still problematic and may depend on etiologic diagnosis to
distinguish infectious from immune-mediated disease. Both pathogenic mechanisms may co …
distinguish infectious from immune-mediated disease. Both pathogenic mechanisms may co …
COVID-19 heart lesions in children: clinical, diagnostic and immunological changes
E Vasichkina, D Alekseeva, I Kudryavtsev… - International journal of …, 2023 - mdpi.com
In the beginning of COVID-19, the proportion of confirmed cases in the pediatric population
was relatively small and there was an opinion that children often had a mild or asymptomatic …
was relatively small and there was an opinion that children often had a mild or asymptomatic …