Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …

We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Viruses are nanosized, genome-filled protein containers with remarkable thermodynamic
and mechanical properties. They form by spontaneous self-assembly inside the crowded …

Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Bacteriophages (phages/viruses) need host bacteria to replicate and propagate. Primarily, a
bacteriophage contains a head/capsid to encapsidate the genetic material. Some phages …

We recently presented a novel class of self-assembled diphenylalanine-based peptide
nanotubes. Here, for the first time, we present their mechanical properties, which we directly …

Partial hydrolysis of the milk protein α-lactalbumin by a protease from Bacillus licheniformis
results in building blocks, which self-assemble into nanometer-sized tubular structures at …

Most viruses use a hollow protein shell, the capsid, to enclose the viral genome. Virus
capsids are large, symmetric oligomers made of many copies of one or a few types of protein …

The elastic properties of capsids of the cowpea chlorotic mottle virus have been examined at
pH 4.8 by nanoindentation measurements with an atomic force microscope. Studies have …