The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Recent advances in microbial ecology and synthetic biology have the potential to mitigate
damage caused by anthropogenic activities that are deleteriously impacting Earth's soil …

Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Living bacteria therapies have been proposed as an alternative approach to treating a broad
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …

Systemic chemotherapy remains the backbone of many cancer treatments. Due to its
untargeted nature and the severe side effects it can cause, numerous nanomedicine …

To support an ever-increasing population, modern agriculture faces numerous challenges
that pose major threats to global food and energy security. Plant-associated microbes, with …

Genetically modified microorganisms (GMMs) can enable a wide range of important
applications including environmental sensing and responsive engineered living materials …

Microbial biocontainment is an essential goal for engineering safe, next-generation living
therapeutics. However, the genetic stability of biocontainment circuits, including kill switches …

Engineered microbes are rapidly being developed for the delivery of therapeutic modalities
to sites of disease. Escherichia coli Nissle 1917 (EcN), a genetically tractable probiotic with …

Our ability to generate bacterial strains with unique and increasingly complex functions has
rapidly expanded in recent times. The capacity for DNA synthesis is increasing and costing …