The diagnosis, investigation and particularly management of bronchiectasis has been
largely empirical and the subject of relatively few controlled clinical trials. There are no clear …

Background Studies have described illness associated with cystic fibrosis (CF) early in life,
but there is no comprehensive accounting of the prevalence and ages of disease …

OBJECTIVES: To determine the prevalence of bronchiectasis in young children with cystic
fibrosis (CF) diagnosed after newborn screening (NBS) and the relationship of …

Background: A sensitive and valid non-invasive marker of early cystic fibrosis (CF) lung
disease is sought. The lung clearance index (LCI) from multiple-breath washout (MBW) is …

OBJECTIVE: To assess pulmonary abnormalities detected by high-resolution computed
tomography (HRCT) in young children with cystic fibrosis (CF) and mild to moderate lung …

For effective clinical management of cystic fibrosis (CF) lung disease it is important to closely
monitor the start and progression of lung damage. The aim of this study was to investigate …

Magnetic resonance imaging (MRI) gains increasing importance in the assessment of cystic
fibrosis (CF) lung disease. The aim of this study was to develop a morpho-functional MR …

Objectives We hypothesized that non-contrast-enhanced PETRA (pointwise encoding time
reduction with radial acquisition) MR (magnetic resonance) sequencing could be an …

Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

The tree-in-bud pattern is commonly seen at thin-section computed tomography (CT) of the
lungs. It consists of small centrilobular nodules of soft-tissue attenuation connected to …