Deconvolution of regulatory mechanisms that drive transcriptional programs in cancer cells
is key to understanding tumor biology. Herein, we present matched transcriptome (scRNA …

At inflammatory sites, cytotoxic agents are released and generated from invading immune
cells and damaged tissue cells. The further fate of the inflammation highly depends on the …

Purpose Early-stage hepatocellular carcinoma (E-HCC) is being diagnosed increasingly,
and in one half of diagnosed patients, recurrence will develop. Thus, it is urgent to identify …

Elafin and its precursor trappin‐2 are known for their contribution to the physiological
mucosal shield against luminal microbes. Such a contribution seems to be particularly …

(1) Background: Biomarkers might play a significant role in predicting the clinical outcomes
of patients with ovarian cancer. By analyzing lipid metabolism genes, future perspectives …

Abstract Glypican-5 (GPC5) is a member of the heparin sulfate proteoglycans. Previous
studies of GPC5 in lung tumorigenesis showed conflicting results. In this study, we confirmed …

Background Elafin is a serine protease inhibitor critical for host defence. We previously
reported that Elafin was associated with the recurrence of early-stage hepatocellular …

Triple-negative breast cancers (TNBCs) are characterized by high rates of recurrence and
poor clinical outcomes. Deregulated E3 ligases are involved in breast cancer pathogenesis …

Radiation therapy is a current standard-of-care treatment and is used widely for GBM
patients. However, radiation therapy still remains a significant barrier to getting a successful …

Regulation of lineage-restricted transcription factors has been shown to influence malignant
transformation in several types of cancer. Whether similar mechanisms are involved in …