Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining
Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …
Strain improvement of Trichoderma harzianum for enhanced biocontrol capacity: Strategies and prospects
Z **ao, Q Zhao, W Li, L Gao, G Liu - Frontiers in microbiology, 2023 - frontiersin.org
In the control of plant diseases, biocontrol has the advantages of being efficient and safe for
human health and the environment. The filamentous fungus Trichoderma harzianum and its …
human health and the environment. The filamentous fungus Trichoderma harzianum and its …
Polystyrene upcycling into fungal natural products and a biocontrol agent
Polystyrene (PS) is one of the most used yet infrequently recycled plastics. Although
manufactured on the scale of 300 million tons per year globally, current approaches toward …
manufactured on the scale of 300 million tons per year globally, current approaches toward …
Transcriptional activation of biosynthetic gene clusters in filamentous fungi
Filamentous fungi are highly productive cell factories, many of which are industrial
producers of enzymes, organic acids, and secondary metabolites. The increasing number of …
producers of enzymes, organic acids, and secondary metabolites. The increasing number of …
Total Heterologous Biosynthesis of Fungal Natural Products in Aspergillus nidulans
Fungal natural products comprise a wide range of bioactive compounds including important
drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have …
drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have …
Anthraquinone-fused enediynes: discovery, biosynthesis and development
X Yan - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to the end of July, 2021 Anthraquinone-fused enediynes (AFEs) are a
subfamily of enediyne natural products. Dynemicin A (DYN A), the first member of the AFE …
subfamily of enediyne natural products. Dynemicin A (DYN A), the first member of the AFE …
A genetic tool to express long fungal biosynthetic genes
L Kirchgaessner, JM Wurlitzer, PS Seibold… - Fungal Biology and …, 2023 - Springer
Abstract Background Secondary metabolites (SMs) from mushroom-forming fungi
(Basidiomycota) and early diverging fungi (EDF) such as Mucoromycota are scarcely …
(Basidiomycota) and early diverging fungi (EDF) such as Mucoromycota are scarcely …
Biosynthesis of Viridicatol in Penicillium palitans Implies a Cytochrome P450-Mediated meta Hydroxylation at a Monoalkylated Benzene Ring
Cyclopenol (1) and viridicatol (6) with m-hydroxyl groups were isolated from a culture of
Penicillium palitans. Genome mining and heterologous expression in Aspergillus nidulans …
Penicillium palitans. Genome mining and heterologous expression in Aspergillus nidulans …
Chemical structures, biological activities, and biosynthetic analysis of secondary metabolites of the Diatrypaceae family: A comprehensive review
SJ Kang, L Zhao, H Wang, JM Gao, J Qi - Mycology, 2024 - Taylor & Francis
The family Diatrypaceae is a less well-known group within the order Xylariales
(Ascomycota). Initially, the focus on its metabolites was related to the pathogenicity of one of …
(Ascomycota). Initially, the focus on its metabolites was related to the pathogenicity of one of …
Mining an O-methyltransferase for de novo biosynthesis of physcion in Aspergillus nidulans
Y Yao, EL Yang, Y Pan, X Shu, G Liu - Applied Microbiology and …, 2023 - Springer
Physcion is one of natural anthraquinones, registered as a novel plant-derived fungicide
due to its excellent prevention of plant disease. However, the current production of physcion …
due to its excellent prevention of plant disease. However, the current production of physcion …