Anthocyanins and proanthocyanidins: Chemical structures, food sources, bioactivities, and product development

Q Qi, M Chu, X Yu, Y **e, Y Li, Y Du, X Liu… - Food Reviews …, 2023 - Taylor & Francis
Anthocyanins and proanthocyanidins are widespread in the plant kingdom and are involved
in important bioactivities, such as antioxidation. These flavonoids can reduce the risk of …

The role of oxidative stress and hypoxia in pancreatic beta-cell dysfunction in diabetes mellitus

PA Gerber, GA Rutter - Antioxidants & redox signaling, 2017 - liebertpub.com
Significance: Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a
disease that currently affects∼ 8% of the adult population worldwide. Pancreatic beta-cell …

Ameliorative effect of curcumin and zinc oxide nanoparticles on multiple mechanisms in obese rats with induced type 2 diabetes

S Abdulmalek, A Eldala, D Awad, M Balbaa - Scientific reports, 2021 - nature.com
The present study was carried out to investigate the therapeutic effect of synthesized
naturally compounds, curcumin nanoparticles (CurNPs) and metal oxide, zinc oxide …

Anthocyanins as promising molecules and dietary bioactive components against diabetes–A review of recent advances

V Gowd, Z Jia, W Chen - Trends in Food Science & Technology, 2017 - Elsevier
Background Diabetes is a metabolic disorder characterized by presence of chronic
hyperglycaemia. Thus, strategies to maintain blood glucose levels are critical for the …

GSK3: a kinase balancing promotion and resolution of inflammation

L Hoffmeister, M Diekmann, K Brand, R Huber - Cells, 2020 - mdpi.com
GSK3 has been implicated for years in the regulation of inflammation and addressed in a
plethora of scientific reports using a variety of experimental (disease) models and …

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Y Bai, W Cui, Y **n, X Miao, MT Barati, C Zhang… - Journal of molecular and …, 2013 - Elsevier
This study was to investigate whether sulforaphane (SFN) can prevent diabetic
cardiomyopathy. Type 1 diabetes was induced in FVB mice by multiple intraperitoneal …

[HTML][HTML] Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway

Y **n, Y Bai, X Jiang, S Zhou, Y Wang, KA Wintergerst… - Redox Biology, 2018 - Elsevier
Aims Activation of nuclear factor erythroid 2-related factor 2 (Nrf2) by sulforaphane (SFN)
protects from, and deletion of the Nrf2 gene exaggerates, diabetic cardiomyopathy …

Cinnamon polyphenol extract inhibits hyperlipidemia and inflammation by modulation of transcription factors in high‐fat diet‐fed rats

Z Tuzcu, C Orhan, N Sahin, V Juturu… - Oxidative medicine and …, 2017 - Wiley Online Library
We evaluated the effects of cinnamon polyphenol extract on hepatic transcription factors
expressions including SREBP‐1c and LXR‐α in rats fed high fat diet (HFD). Twenty‐eight …

[HTML][HTML] Zinc and diabetes: A connection between micronutrient and metabolism

R Ahmad, R Shaju, A Atfi, MS Razzaque - Cells, 2024 - mdpi.com
Diabetes mellitus is a global health problem and a major contributor to mortality and
morbidity. The management of this condition typically involves using oral antidiabetic …

Birth oxidative stress and the development of an antioxidant system in newborn piglets

J Yin, W Ren, G Liu, J Duan, G Yang, L Wu… - Free radical …, 2013 - Taylor & Francis
Birth oxidative stress is an oxidative response to a sudden transition process from maternal
mediated respiration in uterus to autonomous pulmonary respiration outside the uterus …