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[HTML][HTML] Mechanisms and disease consequences of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)
S Wang, SL Friedman - Science translational medicine, 2023 - science.org
Metabolic dysfunction–associated steatohepatitis (MASH) is a severe form of liver disease
that poses a global health threat because of its potential to progress to advanced fibrosis …
that poses a global health threat because of its potential to progress to advanced fibrosis …
Pathophysiological mechanisms of liver injury in COVID‐19
AD Nardo, M Schneeweiss‐Gleixner… - Liver …, 2021 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), caused by the Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …
Mechanisms of fibrosis development in nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease is the most prevalent liver disease worldwide, affecting 20%–
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …
Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion
Y Minami, A Hoshino, Y Higuchi, M Hamaguchi… - Nature …, 2023 - nature.com
Nonalcoholic steatohepatitis (NASH) is a progressive disorder with aberrant lipid
accumulation and subsequent inflammatory and profibrotic response. Therapeutic efforts at …
accumulation and subsequent inflammatory and profibrotic response. Therapeutic efforts at …
[PDF][PDF] Single‐cell transcriptomic analysis reveals a hepatic stellate cell–activation roadmap and myofibroblast origin during liver fibrosis in mice
Background and Aims HSCs and portal fibroblasts (PFs) are the major sources of collagen‐
producing myofibroblasts during liver fibrosis, depending on different etiologies. However …
producing myofibroblasts during liver fibrosis, depending on different etiologies. However …
UCP1 governs liver extracellular succinate and inflammatory pathogenesis
Non-alcoholic fatty liver disease (NAFLD), the most prevalent liver pathology worldwide, is
intimately linked with obesity and type 2 diabetes. Liver inflammation is a hallmark of NAFLD …
intimately linked with obesity and type 2 diabetes. Liver inflammation is a hallmark of NAFLD …
Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis
TM Savage, KT Fortson, K de Los Santos-Alexis… - Immunity, 2024 - cell.com
Production of amphiregulin (Areg) by regulatory T (Treg) cells promotes repair after acute
tissue injury. Here, we examined the function of Treg cells in non-alcoholic steatohepatitis …
tissue injury. Here, we examined the function of Treg cells in non-alcoholic steatohepatitis …
[HTML][HTML] Endothelial cell dysfunction and nonalcoholic fatty liver disease (NAFLD): A concise review
N Nasiri-Ansari, T Androutsakos, CM Flessa, I Kyrou… - Cells, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide. It is strongly associated with obesity, type 2 diabetes (T2DM), and other …
worldwide. It is strongly associated with obesity, type 2 diabetes (T2DM), and other …
Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis
ZY Wang, A Keogh, A Waldt, R Cuttat, M Neri, S Zhu… - Scientific reports, 2021 - nature.com
Fibrosis is characterized by the excessive production of collagen and other extracellular
matrix (ECM) components and represents a leading cause of morbidity and mortality …
matrix (ECM) components and represents a leading cause of morbidity and mortality …