Formins at a glance

D Breitsprecher, BL Goode - Journal of cell science, 2013 - journals.biologists.com
Formins are conserved actin polymerization machines that have instrumental roles in
controlling rearrangements of the actin cytoskeleton and have recently been shown to …

Formin proteins: a domain-based approach

HN Higgs - Trends in biochemical sciences, 2005 - cell.com
Formin proteins are potent regulators of actin dynamics. Most eukaryotes have multiple
formin isoforms, suggesting diverse cellular roles. Formins are modular proteins, containing …

[HTML][HTML] Fifteen formins for an actin filament: a molecular view on the regulation of human formins

A Schönichen, M Geyer - Biochimica et Biophysica Acta (BBA)-Molecular …, 2010 - Elsevier
The regulation of the actin cytoskeleton is a key process for the stability and motility of
eukaryotic cells. Besides the Arp2/3 complex and its nucleation promoting factors, WH2 …

Review of the mechanism of processive actin filament elongation by formins

AS Paul, TD Pollard - Cell motility and the cytoskeleton, 2009 - Wiley Online Library
We review recent structural and biophysical studies of the mechanism of action of formins,
proteins that direct the assembly of unbranched actin filaments for cytokinetic contractile …

The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

F Bartolini, JB Moseley, J Schmoranzer… - Journal of Cell …, 2008 - rupress.org
Formins are a family of ubiquitous, conserved proteins that are implicated in a wide range of
actin-based processes, such as cell polarization, cytokinesis, and cell morphogenesis …

International review of cell and molecular biology

KW Jeon - 2013 - books.google.com
International Review of Cell and Molecular Biology presents current advances and
comprehensive reviews in cell biology--both plant and animal. Articles address structure and …

Transmembrane formins as active cargoes of membrane trafficking

F Cvrčková, R Ghosh, H Kočová - Journal of Experimental …, 2024 - academic.oup.com
Formins are a large, evolutionarily old family of cytoskeletal regulators whose roles include
actin cap** and nucleation, as well as modulation of microtubule dynamics. The plant …

A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization

VC Tam, D Serruto, M Dziejman, W Brieher… - Cell host & …, 2007 - cell.com
We have previously characterized a non-O1, non-O139 Vibrio cholerae strain, AM-19226,
that lacks the known virulence factors but contains components of a type III secretion system …

Signaling to cytoskeletal dynamics during chemotaxis

M Affolter, CJ Weijer - Developmental cell, 2005 - cell.com
We review insights in signaling pathways controlling cell polarization and cytoskeletal
organization during chemotactic movement in Dictyostelium amoebae and neutrophils. We …

A Diaphanous-related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis

A Junemann, V Filić, M Winterhoff, B Nordholz… - Proceedings of the …, 2016 - pnas.org
Phagocytosis and macropinocytosis are Ras-regulated and actin-driven processes that
depend on the dynamic rearrangements of the plasma membrane that protrudes and …