Formation of UV-induced DNA damage contributing to skin cancer development
UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …
Crosstalk between G-quadruplex and ROS
S Wu, L Jiang, L Lei, C Fu, J Huang, Y Hu… - Cell Death & …, 2023 - nature.com
The excessive production of reactive oxygen species (ROS) can lead to single nucleic acid
base damage, DNA strand breakage, inter-and intra-strand cross-linking of nucleic acids …
base damage, DNA strand breakage, inter-and intra-strand cross-linking of nucleic acids …
Nucleic acids as a playground for the computational study of the photophysics and photochemistry of multichromophore assemblies
L Martínez Fernández, F Santoro… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus The interaction between light and multichromophoric assemblies (MCAs) is the
primary event of many fundamental processes, from photosynthesis to organic photovoltaics …
primary event of many fundamental processes, from photosynthesis to organic photovoltaics …
Guanine radicals induced in DNA by low-energy photoionization
E Balanikas, A Banyasz, T Douki… - Accounts of Chemical …, 2020 - ACS Publications
Conspectus Guanine (G) radicals are precursors to DNA oxidative damage, correlated with
carcinogenesis and aging. During the past few years, we demonstrated clearly an intriguing …
carcinogenesis and aging. During the past few years, we demonstrated clearly an intriguing …
External environmental agents influence telomere length and telomerase activity by modulating internal cellular processes: Implications in human aging
SG Fernandes, R Dsouza, E Khattar - Environmental Toxicology and …, 2021 - Elsevier
External environment affects cellular physiological processes and impact the stability of our
genome. The most important structural components of our linear chromosomes which …
genome. The most important structural components of our linear chromosomes which …
Photoinduced intersystem crossing in DNA oxidative lesions and epigenetic intermediates
A Francés-Monerris, M Lineros-Rosa… - Chemical …, 2020 - pubs.rsc.org
The propensity of 5-formyluracil and 5-formylcytosine, ie oxidative lesions and epigenetic
intermediates, in acting as intrinsic DNA photosensitizers is unraveled by using a …
intermediates, in acting as intrinsic DNA photosensitizers is unraveled by using a …
Telomere homeostasis: interplay with magnesium
D Maguire, O Neytchev, D Talwar, D McMillan… - International journal of …, 2018 - mdpi.com
Telomere biology, a key component of the hallmarks of ageing, offers insight into
dysregulation of normative ageing processes that accompany age-related diseases such as …
dysregulation of normative ageing processes that accompany age-related diseases such as …
Contribution of oxidation reactions to photo‐induced damage to cellular DNA
J Cadet, D Angelov, P Di Mascio… - Photochemistry and …, 2024 - Wiley Online Library
This review article is aimed at providing updated information on the contribution of
immediate and delayed oxidative reactions to the photo‐induced damage to cellular …
immediate and delayed oxidative reactions to the photo‐induced damage to cellular …
Impact of double-strand breaks induced by uv radiation on neuroinflammation and neurodegenerative disorders
S Vijayakumar, BV Yesudhason, JL Anandharaj… - Molecular biology …, 2024 - Springer
Exposure to UV affects the development and growth of a wide range of organisms.
Nowadays, researchers are focusing on the impact of UV radiation and its underlying …
Nowadays, researchers are focusing on the impact of UV radiation and its underlying …
Studying the excited electronic states of guanine rich DNA quadruples by quantum mechanical methods: main achievements and perspectives
L Martínez-Fernández, L Esposito, R Improta - … & Photobiological Sciences, 2020 - Springer
The main insights into the photoactivated dynamics of guanine quadruplexes (G4s) recently
provided by quantum mechanical computations are concisely reviewed here. The …
provided by quantum mechanical computations are concisely reviewed here. The …