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Advances in microfluidics: technical innovations and applications in diagnostics and therapeutics
Microfluidics describes the study of systems that operate fluids at miniature scales, often in
microchannels. It is powerful in scaling down biological experiments by many orders of …
microchannels. It is powerful in scaling down biological experiments by many orders of …
Integrated “lab-on-a-chip” microfluidic systems for isolation, enrichment, and analysis of cancer biomarkers
The liquid biopsy has garnered considerable attention as a complementary clinical tool for
the early detection, molecular characterization and monitoring of cancer over the past …
the early detection, molecular characterization and monitoring of cancer over the past …
Engineering Escherichia coli Nissle 1917 as a microbial chassis for therapeutic and industrial applications
Genetically engineered microbes, especially Escherichia coli, have been widely used in the
biosynthesis of proteins and metabolites for medical and industrial applications. As a …
biosynthesis of proteins and metabolites for medical and industrial applications. As a …
Detection of prostate specific antigen in whole blood by microfluidic chip integrated with dielectrophoretic separation and electrochemical sensing
X Wang, X He, Z He, L Hou, C Ge, L Wang, S Li… - Biosensors and …, 2022 - Elsevier
The efficient detection of cancer markers has faced many challenges, such as severe
interference, complicated and time-consuming operation, low sensitivity and so on. In this …
interference, complicated and time-consuming operation, low sensitivity and so on. In this …
Microfluidic strategies for extracellular vesicle isolation: towards clinical applications
Extracellular vesicles (EVs) are double-layered lipid membrane vesicles released by cells.
Currently, EVs are attracting a lot of attention in the biological and medical fields due to their …
Currently, EVs are attracting a lot of attention in the biological and medical fields due to their …
Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer
Extracellular vesicles (EVs) are small lipidic particles packed with proteins, DNA, messenger
RNA and microRNAs of their cell of origin that act as critical players in cell–cell …
RNA and microRNAs of their cell of origin that act as critical players in cell–cell …
Applications of dielectrophoresis in microfluidic-based exosome separation and detection
M Lan, F Yang - Chemical Engineering Journal, 2024 - Elsevier
Exosomes are small vesicles secreted by most cells with contents such as primitive cell
proteins, lipids, and RNAs, which play a key role in cell communication and could be …
proteins, lipids, and RNAs, which play a key role in cell communication and could be …
Advanced manufacturing of nanoparticle formulations of drugs and biologics using microfluidics
Y Shen, H Gwak, B Han - Analyst, 2024 - pubs.rsc.org
Numerous innovative nanoparticle formulations of drugs and biologics, named nano-
formulations, have been developed in the last two decades. However, methods for their …
formulations, have been developed in the last two decades. However, methods for their …
Microfluidic systems for the analysis of blood‐derived molecular biomarkers
Biomarkers are relevant indicators of the physiological state of an individual. Although
biomarkers can be found in diseased tissue and different biofluids, sampling from blood …
biomarkers can be found in diseased tissue and different biofluids, sampling from blood …
Multi‐Phenotypic Exosome Secretion Profiling Microfluidic Platform for Exploring Single‐Cell Heterogeneity
F Song, C Wang, C Wang, J Wang, Y Wu… - Small …, 2022 - Wiley Online Library
Cellular phenotypic and functional heterogeneities have advanced cancer evolution and
treatment resistance. Although exosome‐bound proteins reflect cellular functions, single …
treatment resistance. Although exosome‐bound proteins reflect cellular functions, single …