Transforming growth factor-beta (TGF-β) signaling in cancer-A betrayal within

AB Baba, B Rah, GR Bhat, I Mushtaq… - Frontiers in …, 2022 - frontiersin.org
A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a
significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF …

Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology

R Dutta, R Khalil, R Green, SS Mohapatra… - International journal of …, 2019 - mdpi.com
Ashwagandha (Withania Somnifera, WS), belonging to the family Solanaceae, is an
Ayurvedic herb known worldwide for its numerous beneficial health activities since ancient …

Antioxidant, wound healing potential and in silico assessment of naringin, eicosane and octacosane

A Balachandran, SB Choi, MM Beata, J Małgorzata… - Molecules, 2023 - mdpi.com
1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common
complications of poorly managed diabetes mellitus. The most typical reasons are insufficient …

Inhibition of MMPs and ADAM/ADAMTS

CJ Malemud - Biochemical pharmacology, 2019 - Elsevier
Abstract Matrix metalloproteinases (MMPs), A Disintegrin and Metalloproteinase (ADAM)
and A Disintegrin and Metalloproteinase with Thrombospondin Motif (ADAMTS) are zinc …

The immunomodulatory role of withania somnifera (L.) dunal in inflammatory diseases

HH Alanazi, E Elfaki - Frontiers in pharmacology, 2023 - frontiersin.org
Withania somnifera (L.) Dunal (Solanaceae)(also known as Ashwagandha) is a botanical
drug that has been used for centuries to treat many chronic diseases like high blood …

Withaferin A: a dietary supplement with promising potential as an anti-tumor therapeutic for cancer treatment-pharmacology and mechanisms

Z **ng, A Su, L Mi, Y Zhang, T He, Y Qiu… - Drug Design …, 2023 - Taylor & Francis
Cancer, as the leading cause of death worldwide, poses a serious threat to human health,
making the development of effective tumor treatments a significant challenge. Natural …

Withania somnifera (L.) Dunal: Phytochemistry, structure-activity relationship, and anticancer potential

D Tewari, V Chander, A Dhyani, S Sahu, P Gupta… - Phytomedicine, 2022 - Elsevier
Background Ayurveda is a highly recognized, well-documented, and well-accepted
traditional medicine system. This system utilizes many natural products in various forms for …

Withania somnifera: Progress towards a Pharmaceutical Agent for Immunomodulation and Cancer Therapeutics

VK Kashyap, G Peasah-Darkwah, A Dhasmana… - Pharmaceutics, 2022 - mdpi.com
Chemotherapy is one of the prime treatment options for cancer. However, the key issues
with traditional chemotherapy are recurrence of cancer, development of resistance to …

Single nucleotide polymorphisms (SNPs) in prostate cancer: its implications in diagnostics and therapeutics

KS Allemailem, A Almatroudi… - American journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Prostate cancer is one of the most frequently diagnosed malignancies in developed
countries and approximately 248,530 new cases of prostate cancer are likely to be …

[HTML][HTML] Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives

V Kaur, M Kumar, A Kumar, K Kaur, VS Dhillon… - Biomedicine & …, 2018 - Elsevier
Cancer is a leading cause of disease burden throughout the world. Many cancers develop
as a result of exposure to both lifestyle and environmental factors that are potentially …