Role of oncogenic KRAS in the diagnosis, prognosis and treatment of pancreatic cancer
L Buscail, B Bournet, P Cordelier - Nature reviews Gastroenterology & …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is predicted to be the second most common
cause of death within the next 10 years. The prognosis for this disease is poor despite …
cause of death within the next 10 years. The prognosis for this disease is poor despite …
Polymerase chain reaction in microfluidic devices
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
Current commercial dPCR platforms: Technology and market review
Digital polymerase chain reaction (dPCR) technology has provided a new technique for
molecular diagnostics, with superior advantages, such as higher sensitivity, precision, and …
molecular diagnostics, with superior advantages, such as higher sensitivity, precision, and …
Current and emerging applications of droplet digital PCR in oncology
The clinical management of cancer has evolved in recent years towards more personalized
strategies that require a comprehensive knowledge of the complex molecular features …
strategies that require a comprehensive knowledge of the complex molecular features …
Microfluidic systems for cancer diagnostics
Highlights•Microfluidic platforms enable the analysis and detection of cancer biomarkers.•
Circulating tumor cells can be separated on-chip from whole blood using several …
Circulating tumor cells can be separated on-chip from whole blood using several …
Nanotechnology for ultrafast nucleic acid amplification
Nucleic acid detection has been one of the most valued tools in point-of-care diagnostics
from life science, agriculture, food safety and environmental surveillance, because of its high …
from life science, agriculture, food safety and environmental surveillance, because of its high …
Evaluation of droplet digital PCR and next generation sequencing for characterizing DNA reference material for KRAS mutation detection
L Dong, S Wang, B Fu, J Wang - Scientific reports, 2018 - nature.com
KRAS gene mutations are predictive markers of non-response to anti-epidermal growth
factor receptor. An increasing number of techniques are being developed to detect KRAS …
factor receptor. An increasing number of techniques are being developed to detect KRAS …
Diagnostic value of CA19. 9, circulating tumour DNA and circulating tumour cells in patients with solid pancreatic tumours
D Sefrioui, F Blanchard, E Toure, P Basile… - British journal of …, 2017 - nature.com
Background: The direct comparison of CA19. 9, circulating tumour cells (CTCs) and
circulating tumour DNA (ctDNA) using endoscopic ultrasound-guided fine needle aspiration …
circulating tumour DNA (ctDNA) using endoscopic ultrasound-guided fine needle aspiration …
Lab-on-a-chip platforms for detection of cardiovascular disease and cancer biomarkers
Cardiovascular disease (CVD) and cancer are two leading causes of death worldwide. CVD
and cancer share risk factors such as obesity and diabetes mellitus and have common …
and cancer share risk factors such as obesity and diabetes mellitus and have common …
Comparison of droplet digital PCR and conventional quantitative PCR for measuring EGFR gene mutation
BO Zhang, CW Xu, Y Shao… - Experimental and …, 2015 - spandidos-publications.com
Early detection of epidermal growth factor receptor (EGFR) mutation, particularly EGFR
T790M mutation, is of clinical significance. The aim of the present study was to compare the …
T790M mutation, is of clinical significance. The aim of the present study was to compare the …