Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary
kidney disease and one of the most common causes of end-stage kidney disease. Multiple …

Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal,
monogenic disorder. It is associated with large interfamilial and intrafamilial variability, which …

Data indicate significant phenotypic and genotypic overlap, plus a common pathogenesis,
between two groups of inherited disorders, autosomal dominant polycystic kidney diseases …

A number of inherited disorders result in renal cyst development. The most common form,
autosomal dominant polycystic kidney disease (ADPKD), is a disorder most often diagnosed …

Background Autosomal dominant polycystic kidney disease (ADPKD) is characterized by
progressive enlargement of cyst-filled kidneys. Methods In a three-year study, we measured …

In the past, the treatment of autosomal dominant polycystic kidney disease (ADPKD) has
been limited to the management of its symptoms and complications. Recently, the US Food …

The incidence of chronic kidney diseases is increasing worldwide, and these conditions are
emerging as a major public health problem. While genetic factors contribute to susceptibility …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited
cause of kidney failure, accounting for 5%-10% of cases. Predicting which patients with …

Autosomal dominant polycystic kidney disease (ADPKD) caused by mutations in PKD1 is
significantly more severe than PKD2. Typically, ADPKD presents in adulthood but is rarely …

Autosomal dominant polycystic kidney disease (PKD) is a hereditary condition characterized
by the progressive enlargement of innumerable renal cysts that contribute to life-altering …