Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …

Chronic wounds have become one of the most important issues for healthcare systems and
are a leading cause of death worldwide. Wound dressings are necessary to facilitate wound …

Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …

Cell-matrix interactions play a critical role in tissue repair and regeneration. With gradual
uncovering of substrate mechanical characteristics that can affect cell-matrix interactions …

Cell adhesion is a basic requirement for anchorage-dependent cells to survive on the matrix.
It is the first step in a series of cell activities, such as cell diffusion, migration, proliferation …

The encapsulation of cells within gel‐phase materials to form bioinks offers distinct
advantages for next‐generation 3D bioprinting. 3D bioprinting has emerged as a promising …

Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Hydrogels have emerged in various biomedical applications, including tissue engineering
and medical devices, due to their ability to imitate the natural extracellular matrix (ECM) of …