High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …

Hypertension is the most common chronic disease in the world, yet the precise cause of
elevated blood pressure often cannot be determined. Animal models have been useful for …

Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …

Ischemic stroke is the major type of cerebrovascular disease usually resulting in death or
disability among the aging population globally. Oxidative stress has been closely linked with …

Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …

The gut microbiota plays a critical role in maintaining physiological homeostasis. This study
was designed to evaluate whether gut microbial composition affects hypertension. 16S …

Hypertension is a leading risk factor for disease burden worldwide. The kidneys, which have
a high specific metabolic rate, play an essential role in the long-term regulation of arterial …

Emerging data indicate a correlation between gut microbial composition and cardiovascular
disease including hypertension. The host's diet greatly affects microbial composition and …

Early diagnosis of chronic kidney disease (CKD) and constant monitoring to guide optimal
intervention is critical to prevent renal failure and other critical diseases. However, the …

Significance: Renal oxidative stress can be a cause, a consequence, or more often a
potentiating factor for hypertension. Increased reactive oxygen species (ROS) in the kidney …