The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly
applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the …

Abstract The use of 'Click Reaction'for Cu (I) catalyzed azide–alkyne cycloaddition (CuAAC)
has emerged as one of the most powerful tools for the synthesis of library of organic …

Immuno-PCR combines specific antibody-based protein detection with the sensitivity of PCR-
based quantification through the use of antibody-DNA conjugates. The production of such …

The clinical success of linezolid for treating Gram-positive infections paired with the high
conservation of bacterial ribosomes predicts that if oxazolidinones were engineered to …

Electro-click methodology was employed to prepare an electrochemical immunosensor for
the cytokine interleukin 1β (IL-1β). The strategy involved binding of ethynylated IgG to azide …

Antibody-conjugated nanoparticles (NPs) have attracted great attention in diagnostic and
therapeutic applications due to their high sensitivity and specificity for biotargets, as well as …

An electrochemical immunosensor for the determination of the multifunctional Transforming
Growth Factor β1 (TGF-β1) cytokine has been prepared using multi-walled carbon nanotube …

Currently, the chemistry of alpha-oxoaldehydes (α-oxo-ALD) is a versatile and useful tool in
the field of bioconjugation of peptides and proteins. The combination of smart materials with …

Antibodies are extensively used in research, diagnostics, and therapy, and for many
applications the antibodies need to be labeled. Labeling is typically performed by using …

Herein, the synthesis and characterization of orthogonal dendrons decorated with multiple
units of fluorescent and a chemoselective group at a focal point, followed by specific …