Scorpion venom components as potential candidates for drug development
Scorpions are well known for their dangerous stings that can result in severe consequences
for human beings, including death. Neurotoxins present in their venoms are responsible for …
for human beings, including death. Neurotoxins present in their venoms are responsible for …
Coming of age: orphan genes in plants
Sizable minorities of protein-coding genes from every sequenced eukaryotic and prokaryotic
genome are unique to the species. These so-called 'orphan genes' may evolve de novo from …
genome are unique to the species. These so-called 'orphan genes' may evolve de novo from …
Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel
A Banerjee, A Lee, E Campbell, R MacKinnon - Elife, 2013 - elifesciences.org
Pore-blocking toxins inhibit voltage-dependent K+ channels (Kv channels) by plugging the
ion-conduction pathway. We have solved the crystal structure of paddle chimera, a Kv …
ion-conduction pathway. We have solved the crystal structure of paddle chimera, a Kv …
Scorpion venom peptides with no disulfide bridges: a review
A Almaaytah, Q Albalas - Peptides, 2014 - Elsevier
Scorpion venoms are rich sources of biologically active peptides that are classified into
disulfide-bridged peptides (DBPs) and non-disulfide-bridged peptides (NDBPs). DBPs are …
disulfide-bridged peptides (DBPs) and non-disulfide-bridged peptides (NDBPs). DBPs are …
The biochemical toxin arsenal from ant venoms
Ants (Formicidae) represent a taxonomically diverse group of hymenopterans with over
13,000 extant species, the majority of which inject or spray secretions from a venom gland …
13,000 extant species, the majority of which inject or spray secretions from a venom gland …
A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts
Scorpions are an ancient and diverse venomous lineage, with over 2200 currently
recognized species. Only a small fraction of scorpion species are considered harmful to …
recognized species. Only a small fraction of scorpion species are considered harmful to …
Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities
X Guo, C Ma, Q Du, R Wei, L Wang, M Zhou, T Chen… - Biochimie, 2013 - Elsevier
Here we report two novel 17-mer amidated linear peptides (TsAP-1 and TsAP-2) whose
structures were deduced from cDNAs cloned from a venom-derived cDNA library of the …
structures were deduced from cDNAs cloned from a venom-derived cDNA library of the …
Scorpions from Mexico: From species diversity to venom complexity
Scorpions are among the oldest terrestrial arthropods, which are distributed worldwide,
except for Antarctica and some Pacific islands. Scorpion envenomation represents a public …
except for Antarctica and some Pacific islands. Scorpion envenomation represents a public …
Natural biomaterials from biodiversity for healthcare applications
E Insuasti‐Cruz, V Suárez‐Jaramillo… - Advanced …, 2022 - Wiley Online Library
Natural biomaterials originating during the growth cycles of all living organisms have been
used for many applications. They span from bioinert to bioactive materials including …
used for many applications. They span from bioinert to bioactive materials including …
Venom Proteomics of Indonesian King Cobra, Ophiophagus hannah: Integrating Top-Down and Bottom-Up Approaches
D Petras, P Heiss, RD Süssmuth… - Journal of proteome …, 2015 - ACS Publications
We report on the first application of top-down mass spectrometry in snake venomics. De
novo sequence tags generated by, and ProSight Lite supported analysis of, combined …
novo sequence tags generated by, and ProSight Lite supported analysis of, combined …