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Role of neuroinflammation in neurodegeneration development
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …
Pathophysiology of RAGE in inflammatory diseases
H Dong, Y Zhang, Y Huang, H Deng - Frontiers in Immunology, 2022 - frontiersin.org
The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
pattern recognition receptor capable of binding to a range of structurally diverse ligands …
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state
Idiopathic Parkinson's disease is characterized by a progressive loss of dopaminergic
neurons, but the exact disease aetiology remains largely unknown. To date, Parkinson's …
neurons, but the exact disease aetiology remains largely unknown. To date, Parkinson's …
Parkinson disease and the immune system—associations, mechanisms and therapeutics
Multiple lines of evidence indicate that immune system dysfunction has a role in Parkinson
disease (PD); this evidence includes clinical and genetic associations between autoimmune …
disease (PD); this evidence includes clinical and genetic associations between autoimmune …
[PDF][PDF] Damage-associated molecular patterns in inflammatory diseases
JS Roh, DH Sohn - Immune network, 2018 - synapse.koreamed.org
Damage-associated molecular patterns (DAMPs) are endogenous danger molecules that
are released from damaged or dying cells and activate the innate immune system by …
are released from damaged or dying cells and activate the innate immune system by …
Dietary polyphenols: Regulate the advanced glycation end products-RAGE axis and the microbiota-gut-brain axis to prevent neurodegenerative diseases
Y Li, Y Peng, Y Shen, Y Zhang, L Liu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs) are formed in non-enzymatic reaction, oxidation,
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …
rearrangement and cross-linking between the active carbonyl groups of reducing sugars …
Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury
Advanced glycation end products (AGEs) are potentially harmful and heterogeneous
molecules derived from nonenzymatic glycation. The pathological implications of AGEs are …
molecules derived from nonenzymatic glycation. The pathological implications of AGEs are …
The link between neuroinflammation and the neurovascular unit in synucleinopathies
The neurovascular unit (NVU) is composed of vascular cells, glial cells, and neurons. As a
fundamental functional module in the central nervous system, the NVU maintains …
fundamental functional module in the central nervous system, the NVU maintains …
The S100B story: from biomarker to active factor in neural injury
S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …
The S100B protein: a multifaceted pathogenic factor more than a biomarker
S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …