Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Abstract Background/Objectives: Biochemical recurrence (BCR) after radical prostatectomy
(RP) is a significant predictor of distal metastases and mortality in prostate cancer (PCa) …

While hundreds of cancer-associated long noncoding RNAs (lncRNAs) have been
discovered, their functional role in cancer cells is still largely a mystery. An increasing …

Importance Abiraterone acetate and enzalutamide are recommended as preferred
treatments for metastatic castration-resistant prostate cancer (mCRPC), but differences in …

Importance Men with limited life expectancy (LE) have historically been overtreated for
prostate cancer despite clear guideline recommendations. With increasing use of active …

Background and objective Advances in molecular diagnostics have ushered in a new era for
patients with prostate, renal, and urothelial cancers, with novel radiographic and molecular …

Lineage plasticity and histologic transformation from prostate adenocarcinoma to
neuroendocrine (NE) prostate cancer (NEPC) occur in up to 15% to 20% of patients with …

High-risk localized prostate cancer remains a lethal disease with high rates of recurrence,
metastases and death, despite attempts at curative local treatment including surgery …

Purpose Recent advancements in the management of biochemical recurrence (BCR)
following local treatment for prostate cancer (PCa), including the use of androgen receptor …

Major advances in prostate cancer diagnosis, staging, and management have occurred over
the past decade, largely due to our improved understanding of the technical aspects and …