Systemic immunoglobulin light chain amyloidosis

G Merlini, A Dispenzieri, V Sanchorawala… - Nature reviews Disease …, 2018 - nature.com
Systemic immunoglobulin light chain amyloidosis is a protein misfolding disease caused by
the conversion of immunoglobulin light chains from their soluble functional states into highly …

Monoclonal gammopathy of undetermined significance

TH Mouhieddine, LD Weeks… - Blood, The Journal of …, 2019 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma
cell dyscrasia that consistently precedes multiple myeloma (MM) with a 1% risk of …

Guidelines for high dose chemotherapy and stem cell transplantation for systemic AL amyloidosis: EHA-ISA working group guidelines

V Sanchorawala, M Boccadoro, M Gertz, U Hegenbart… - Amyloid, 2022 - Taylor & Francis
AL amyloidosis is a systemic amyloidosis and is associated with an underlying plasma cell
dyscrasia. High dose intravenous melphalan and autologous stem cell transplantation was …

Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2018

MA Gertz - Blood cancer journal, 2018 - nature.com
Immunoglobulin light chain amyloidosis (AL) should be considered in any patient that
presents to a cancer care provider with nephrotic range proteinuria, heart failure with …

Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2021

M Hasib Sidiqi, MA Gertz - Blood cancer journal, 2021 - nature.com
Immunoglobulin light chain amyloidosis (AL) commonly presents with nephrotic range
proteinuria, heart failure with preserved ejection fraction, nondiabetic peripheral neuropathy …

Monoclonal gammopathy of renal significance (MGRS): Real‐world data on outcomes and prognostic factors

A Gozzetti, A Guarnieri, E Zamagni… - American Journal of …, 2022 - Wiley Online Library
Monoclonal gammopathy of renal significance (MGRS) is a recognized clinical entity.
Literature regarding treatment and its outcomes in MGRS is sparse due to the rarity and …

Monoclonal gammopathy of undetermined significance (MGUS)—Not so asymptomatic after all

OC Lomas, TH Mouhieddine, S Tahri, IM Ghobrial - Cancers, 2020 - mdpi.com
Monoclonal Gammopathy of Undetermined Significance (MGUS) is considered to be a
benign precursor condition that may progress to a lymphoproliferative disease or multiple …

Monoclonal gammopathy of renal significance: Multidisciplinary approach to diagnosis and treatment

S Karam, M Haidous, I Abou Dalle… - Critical reviews in …, 2023 - Elsevier
Monoclonal gammopathy of renal significance (MGRS) is a hemato-nephrological term
referring to a heterogeneous group of kidney disorders characterized by direct or indirect …

Treatment of patients with monoclonal gammopathy of clinical significance

DF Moreno, L Rosiñol, MT Cibeira, J Bladé… - Cancers, 2021 - mdpi.com
Simple Summary Monoclonal gammopathy of clinical significance (MGCS) is a recently
recognized clinical-pathological entity. Symptoms are caused by the presence of a …

Renal AL Amyloidosis: Updates on Diagnosis, Staging, and Management

A Shafqat, H Elmaleh, A Mushtaq, Z Firdous… - Journal of Clinical …, 2024 - mdpi.com
AL amyloidosis is caused by the excessive production of nonfunctional immunoglobulins,
leading to the formation of amyloid fibrils that damage vital organs, especially the heart and …