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Large-scale neural recordings call for new insights to link brain and behavior
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …
facing the challenge of connecting these brain-wide neural recordings to computation and …
Two-photon calcium imaging of neuronal activity
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …
activity in the intact brain. It is based on the principle that, when neurons fire action …
[HTML][HTML] Fast and sensitive GCaMP calcium indicators for imaging neural populations
Calcium imaging with protein-based indicators, is widely used to follow neural activity in
intact nervous systems, but current protein sensors report neural activity at timescales much …
intact nervous systems, but current protein sensors report neural activity at timescales much …
A microscale soft ionic power source modulates neuronal network activity
Bio-integrated devices need power sources to operate,. Despite widely used technologies
that can provide power to large-scale targets, such as wired energy supplies from batteries …
that can provide power to large-scale targets, such as wired energy supplies from batteries …
Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids
Three-dimensional (3D), submillimeter-scale constructs of neural cells, known as cortical
spheroids, are of rapidly growing importance in biological research because these systems …
spheroids, are of rapidly growing importance in biological research because these systems …
Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound
Electrical stimulation is a fundamental tool in studying neural circuits, treating neurological
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …
Neuroscience needs network science
The brain is a complex system comprising a myriad of interacting neurons, posing significant
challenges in understanding its structure, function, and dynamics. Network science has …
challenges in understanding its structure, function, and dynamics. Network science has …
[HTML][HTML] Progress in brain computer interface: Challenges and opportunities
Brain computer interfaces (BCI) provide a direct communication link between the brain and a
computer or other external devices. They offer an extended degree of freedom either by …
computer or other external devices. They offer an extended degree of freedom either by …
Genetic dissection of neural circuits: a decade of progress
Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …
Fluorescence imaging of large-scale neural ensemble dynamics
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …
thousands of individual neurons, identified genetically or by their connectivity, across …