Large-scale neural recordings call for new insights to link brain and behavior

AE Urai, B Doiron, AM Leifer, AK Churchland - Nature neuroscience, 2022 - nature.com
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Two-photon calcium imaging of neuronal activity

C Grienberger, A Giovannucci, W Zeiger… - Nature Reviews …, 2022 - nature.com
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …

[HTML][HTML] Fast and sensitive GCaMP calcium indicators for imaging neural populations

Y Zhang, M Rózsa, Y Liang, D Bushey, Z Wei, J Zheng… - Nature, 2023 - nature.com
Calcium imaging with protein-based indicators, is widely used to follow neural activity in
intact nervous systems, but current protein sensors report neural activity at timescales much …

A microscale soft ionic power source modulates neuronal network activity

Y Zhang, J Riexinger, X Yang, E Mikhailova, Y **… - Nature, 2023 - nature.com
Bio-integrated devices need power sources to operate,. Despite widely used technologies
that can provide power to large-scale targets, such as wired energy supplies from batteries …

Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids

Y Park, CK Franz, H Ryu, H Luan, KY Cotton… - Science …, 2021 - science.org
Three-dimensional (3D), submillimeter-scale constructs of neural cells, known as cortical
spheroids, are of rapidly growing importance in biological research because these systems …

Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound

M Han, E Yildiz, U Bozuyuk, A Aydin, Y Yu… - Nature …, 2024 - nature.com
Electrical stimulation is a fundamental tool in studying neural circuits, treating neurological
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …

Neuroscience needs network science

DL Barabási, G Bianconi, E Bullmore… - Journal of …, 2023 - jneurosci.org
The brain is a complex system comprising a myriad of interacting neurons, posing significant
challenges in understanding its structure, function, and dynamics. Network science has …

[HTML][HTML] Progress in brain computer interface: Challenges and opportunities

S Saha, KA Mamun, K Ahmed, R Mostafa… - Frontiers in systems …, 2021 - frontiersin.org
Brain computer interfaces (BCI) provide a direct communication link between the brain and a
computer or other external devices. They offer an extended degree of freedom either by …

Genetic dissection of neural circuits: a decade of progress

L Luo, EM Callaway, K Svoboda - Neuron, 2018 - cell.com
Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …

Fluorescence imaging of large-scale neural ensemble dynamics

TH Kim, MJ Schnitzer - Cell, 2022 - cell.com
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …