Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can
have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent …

Daily dietary potassium (K+) intake may be as large as the extracellular K+ pool. To avoid
acute hyperkalemia, rapid removal of K+ from the extracellular space is essential. This is …

A dietary potassium load induces a rapid kaliuresis and natriuresis, which may occur even
before plasma potassium and aldosterone (aldo) levels increase. Here we sought to gain …

The discovery of four genes responsible for pseudohypoaldosteronism type II, or familial
hyperkalemic hypertension, which features arterial hypertension with hyperkalemia and …

Potassium homeostasis has a very high priority because of its importance for membrane
potential. Although extracellular K+ is only 2% of total body K+, our physiology was …

Activation of the intrarenal renin-angiotensin system (RAS) can elicit hypertension
independently from the systemic RAS. However, the precise mechanisms by which …

Transmembrane potassium (K) gradients are key determinants of membrane potential that
can modulate action potentials, control muscle contractility, and influence ion channel and …

The development of the immunoblot to detect and characterize a protein with an antisera,
even in a crude mixture, was a breakthrough with wide-ranging and unpredictable …

Dietary potassium loading results in rapid kaliuresis, natriuresis, and diuresis associated
with reduced phosphorylation (p) of the distal tubule Na+-Cl− cotransporter (NCC) …

Dietary potassium (K+) supplementation is associated with a lowering effect in blood
pressure (BP), but not all studies agree. Here, we examined the effects of short-and long …