From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: recent advances in our understanding of disorders of …

MA Bruno, A Vanhaudenhuyse, A Thibaut… - Journal of …, 2011 - Springer
Functional neuroimaging and electrophysiology studies are changing our understanding of
patients with coma and related states. Some severely brain damaged patients may show …

Coma and consciousness: paradigms (re) framed by neuroimaging

S Laureys, ND Schiff - Neuroimage, 2012 - Elsevier
The past 15years have provided an unprecedented collection of discoveries that bear upon
our scientific understanding of recovery of consciousness in the human brain following …

European Academy of Neurology guideline on the diagnosis of coma and other disorders of consciousness

D Kondziella, A Bender, K Diserens… - European journal of …, 2020 - Wiley Online Library
Background and purpose Patients with acquired brain injury and acute or prolonged
disorders of consciousness (DoC) are challenging. Evidence to support diagnostic decisions …

The reliability of the Glasgow Coma Scale: a systematic review

FCM Reith, R Van den Brande, A Synnot, R Gruen… - Intensive care …, 2016 - Springer
Abstract Introduction The Glasgow Coma Scale (GCS) provides a structured method for
assessment of the level of consciousness. Its derived sum score is applied in research and …

Sepsis associated encephalopathy

N Chaudhry, AK Duggal - Advances in medicine, 2014 - Wiley Online Library
Sepsis associated encephalopathy (SAE) is a common but poorly understood neurological
complication of sepsis. It is characterized by diffuse brain dysfunction secondary to infection …

A precision medicine framework for classifying patients with disorders of consciousness: Advanced Classification of Consciousness Endotypes (ACCESS)

D Kondziella, DK Menon, R Helbok, L Naccache… - Neurocritical Care, 2021 - Springer
Background Consciousness in patients with brain injury is traditionally assessed based on
semiological evaluation at the bedside. This classification is limited because of low …

The effect of age on Glasgow Coma Scale score in patients with traumatic brain injury

K Salottolo, AS Levy, DS Slone, CW Mains… - JAMA …, 2014 - jamanetwork.com
Importance The Glasgow Coma Scale (GCS) is used frequently to define the extent of
neurologic injury in patients with a traumatic brain injury (TBI). Whether age affects the …

Diagnosis of reversible causes of coma

JA Edlow, A Rabinstein, SJ Traub, EFM Wijdicks - The Lancet, 2014 - thelancet.com
Because coma has many causes, physicians must develop a structured, algorithmic
approach to diagnose and treat reversible causes rapidly. The three main mechanisms of …

Factors influencing the reliability of the Glasgow Coma Scale: a systematic review

FCM Reith, A Synnot, R van den Brande, RL Gruen… - …, 2017 - journals.lww.com
BACKGROUND: The Glasgow Coma Scale (GCS) characterizes patients with diminished
consciousness. In a recent systematic review, we found overall adequate reliability across …

A comparison of the Glasgow Coma Scale score with full outline of unresponsiveness scale to predict patients' traumatic brain injury outcomes in intensive care units

R Jalali, M Rezaei - Critical care research and practice, 2014 - Wiley Online Library
Background. Neurological assessment is an essential element of early warning scores used
to recognize critically ill patients. We compared the performance of the Glasgow Coma Scale …