Variation in recombination frequency and distribution across eukaryotes: patterns and processes
Recombination, the exchange of DNA between maternal and paternal chromosomes during
meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms …
meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms …
Understanding the genetic basis of variation in meiotic recombination: past, present, and future
SE Johnston - Molecular Biology and Evolution, 2024 - academic.oup.com
Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …
required for proper chromosome segregation and plays important role in adaptation and the …
De novo assembly of the cattle reference genome with single-molecule sequencing
Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
Inbreeding depression due to recent and ancient inbreeding in Dutch Holstein–Friesian dairy cattle
Background Inbreeding decreases animal performance (inbreeding depression), but not all
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …
[HTML][HTML] Symposium review: Possibilities in an age of genomics: The future of selection indices
Selective breeding has been practiced since domestication, but early breeders commonly
selected on appearance (eg, coat color) rather than performance traits (eg, milk yield). A …
selected on appearance (eg, coat color) rather than performance traits (eg, milk yield). A …
A publicly available repository of ROH islands reveals signatures of selection in different livestock and pet species
Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
[HTML][HTML] Invited review: Inbreeding in the genomics era: Inbreeding, inbreeding depression, and management of genomic variability
Traditionally, pedigree-based relationship coefficients have been used to manage the
inbreeding and degree of inbreeding depression that exists within a population. The …
inbreeding and degree of inbreeding depression that exists within a population. The …
The era of the ARG: An introduction to ancestral recombination graphs and their significance in empirical evolutionary genomics
In the presence of recombination, the evolutionary relationships between a set of sampled
genomes cannot be described by a single genealogical tree. Instead, the genomes are …
genomes cannot be described by a single genealogical tree. Instead, the genomes are …
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle
Inbred animals were historically chosen for genome analysis to circumvent assembly issues
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
caused by haplotype variation but this resulted in a composite of the two genomes. Here we …
Meta‐analysis of chromosome‐scale crossover rate variation in eukaryotes and its significance to evolutionary genomics
Understanding the distribution of crossovers along chromosomes is crucial to evolutionary
genomics because the crossover rate determines how strongly a genome region is …
genomics because the crossover rate determines how strongly a genome region is …