Collagen—emerging collagen based therapies hit the patient

EA Abou Neel, L Bozec, JC Knowles, O Syed… - Advanced drug delivery …, 2013 - Elsevier
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

The current role of steroids in acute spinal cord injury

M Bydon, J Lin, M Macki, ZL Gokaslan, A Bydon - World neurosurgery, 2014 - Elsevier
Background Acute spinal cord injury (ASCI) is a catastrophic event that can profoundly affect
the trajectory of a patient's life. Debate continues over the pharmacologic management of …

Immunomodulatory and angiogenic responses induced by graphene oxide scaffolds in chronic spinal hemisected rats

E López-Dolado, A González-Mayorga, MC Gutiérrez… - Biomaterials, 2016 - Elsevier
Attractive physic-chemical features of graphene oxide (GO) and promising results in vitro
with neural cells encourage its exploration for biomedical applications including neural …

Neurite outgrowth of dorsal root ganglia neurons is enhanced on aligned nanofibrous biopolymer scaffold with carbon nanotube coating

GZ **, M Kim, US Shin, HW Kim - Neuroscience letters, 2011 - Elsevier
Nerve regeneration and functional recovery have been a major issue following injury of
nerve tissues. Electrospun nanofibers are known to be suitable scaffolds for neural tissue …

Self-assembling peptide gels promote angiogenesis and functional recovery after spinal cord injury in rats

JY Hong, SH Kim, Y Seo, J Jeon… - Journal of tissue …, 2022 - journals.sagepub.com
Spinal cord injury (SCI) leads to disruption of the blood–spinal cord barrier, hemorrhage,
and tissue edema, which impair blood circulation and induce ischemia. Angiogenesis after …

Microglia response and in vivo therapeutic potential of methylprednisolone‐loaded dendrimer nanoparticles in spinal cord injury

SR Cerqueira, JM Oliveira, NA Silva, H Leite‐Almeida… - Small, 2013 - Wiley Online Library
The control and manipulation of cells that trigger secondary mechanisms following spinal
cord injury (SCI) is one of the first opportunities to minimize its highly detrimental outcomes …

Electroconductive and mechano-competent PUCL@ CNT nanohybrid scaffolds guiding neuronal specification of neural stem/progenitor cells

YM Li, KD Patel, YK Han, SM Hong, YX Meng… - Chemical Engineering …, 2023 - Elsevier
Diseased or injured nervous systems lead to lifelong disability and even death due to their
limited self-repair and regenerative capability. For successful neuronal regeneration and …

MiR‐30a‐5p ameliorates spinal cord injury‐induced inflammatory responses and oxidative stress by targeting Neurod 1 through MAPK/ERK signalling

X Fu, YI Shen, W Wang, X Li - Clinical and Experimental …, 2018 - Wiley Online Library
Spinal cord injury (SCI) is a major disability requiring more effective treatment than is
currently available. Micro RNA s have been shown to effectively regulate gene expression at …

Maximum principal strain correlates with spinal cord tissue damage in contusion and dislocation injuries in the rat cervical spine

CM Russell, AM Choo, W Tetzlaff, TE Chung… - Journal of …, 2012 - liebertpub.com
The heterogeneity of the primary mechanical mechanism of spinal cord injury (SCI) is not
currently used to tailor treatment strategies because the effects of these distinct patterns of …

Directing neural differentiation of mesenchymal stem cells by carboxylated multiwalled carbon nanotubes

YS Chen, GH Hsiue - Biomaterials, 2013 - Elsevier
The use of carbon nanotubes (CNTs) to promote neural differentiation is well known.
However, most studies have focused on the effect of CNT-derived composites or CNT-based …